In the United States, Clostridioides difficile infection (CDI) is the leading cause of healthcare-
associated infection, affecting nearly half a million people and resulting in more than 20,000 …

Clostridioides difficile infection (CDI) is the most common nosocomial bacterial infection in
the United States, which makes it a joint health care issue for both medical and surgical …

Clostridioides difficile is the most common cause of healthcare-associated diarrhea. Disease
complications as well as recurrent infections contribute significantly to morbidity and …

Clostridioides difficile is a spore forming bacterium leading to significant morbidity and
mortality amongst hospitalized as well as non-hospitalized patients in the United States …

Introduction The gut microbiome is implicated in Clostridioides difficile infection (CDI) and
recurrent CDI (rCDI). Areas covered This review covers the mechanisms by which …

Clostridioides difficile (C. difficile) is a gram-positive, anaerobic spore-forming bacterium and
a major cause of antibiotic-associated diarrhea. Humans are naturally resistant to C. difficile …

Oral vancomycin and metronidazole, though they are the therapeutic choice for
Clostridioides difficile infections (CDIs), also markedly disturb microbiota, leading to a …

AIMS OF THE STUDY Clostridioides difficile infection (CDI) is associated with high
morbidity, recurrence rates and mortality. We assessed the local epidemiology, treatment …

New therapies to treat and prevent Clostridioides difficile infections (CDI) are needed. CDI
requires antibiotic therapy, but this can disrupt gut microbiomes and increase susceptibility …

Clostridioides (formerly Clostridium) difficile infection (CDI) is the most common cause of
health care–associated infectious diarrhea in the developed world. The Infectious Diseases …