RECENT work suggests that an autosomal dominant gene for schizophrenia may be located
on the 5q11-q13 region of chromosome 5 (refs 1 and 2): a report of schizophrenia …

Schizophrenia is a heterogenous disorder that is phenomenologically characterised by a
combination of negative, positive, and cognitive symptoms with variable expression in the …

Research into the genomics of schizophrenia promises much, but so far is resplendent with
failures to replicate, and has yielded little of therapeutic potential. Within our bodies resides …

Schizophrenia is a complex disorder caused by both genetic and environmental factors.
Using 9,087 affected individuals, 12,171 controls and 915,354 imputed SNPs from the …

The search for the genetic architecture of schizophrenia has employed multiple, often
converging strategies. One such strategy entails the use of tracing the heritability and …

Background A recent analysis of 25 historical candidate gene polymorphisms for
schizophrenia in the largest genome-wide association study conducted to date suggested …

We have discovered two genes, RSRC1 and ARHGAP18, associated with schizophrenia
and in an independent study provided additional support for this association. We have both …

We performed integrated gene coexpression network analysis on two large microarray-
based brain gene expression data sets generated from the prefrontal cortex obtained post …

Importance Schizophrenia is accompanied by a loss of integrity of white matter connections
that compose the structural brain network, which is believed to diminish the efficiency of …

Research on the genetic basis of mental disorders crossed a major watershed this summer.
For the first time, specific genes have been discovered that influence susceptibility to …