Microglia, the dynamic innate immune cells of the central nervous system, become activated
in epilepsy. The process of microglial activation in epilepsy results in the creation of an …

Background Epilepsy is one of the most common brain disorder and, despite the possible
use of several therapeutic options, many patients continue to have seizures for their entire …

Background and Purpose A non‐psychoactive phytocannabinoid, cannabidiol (CBD), shows
promising results as an effective potential antiepileptic drug in some forms of refractory …

The present study reports the behavioral, electrophysiological, and neuropathological
effects of cannabidiol (CBD), a major non-psychotropic constituent of Cannabis sativa, in the …

Anticonvulsant effects of cannabidiol (CBD), a nonpsychoactive cannabinoid, have not been
investigated in the juvenile brain. We hypothesized that CBD would attenuate epileptiform …

Objective Epilepsy is a progressive neurological disease characterized by recurrent
seizures and behavioral comorbidities. We investigated the antiseizure effect of cannabidiol …

Presently there is no drug therapy for curing epilepsy. Despite many advancements in
epilepsy research, nearly 30% of people with epilepsy remain refractory to current …

Abstract The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt)/mechanistic
target of rapamycin (mTOR) signaling pathway has been associated with several …

The hippocampus is one of the most susceptible regions in the brain to be distraught with
status epilepticus (SE) induced injury. SE can occur from numerous causes and is more …

Anecdotal reports of the benefits of cannabis and its components in the treatment of epilepsy
have been reported for millennia. However, only recently randomized controlled trial data in …