Although the critical role for epigenetic mechanisms in development and cell differentiation
has long been appreciated, recent evidence reveals that these mechanisms are also …

Epigenetic regulation has been long considered to be a critical mechanism in the control of
key aspects of cellular functions such as cell division, growth, and cell fate determination …

Discoveries concerning the molecular mechanisms of cell differentiation and development
have dictated the definition of a new sub-discipline of genetics known as epigenetics …

The role of epigenetic mechanisms in control of gene expression during mammalian
development is well established. Associations between specific DNA or histone …

Brain-derived neurotrophic factor (bdnf) is one of numerous gene products necessary for
long-term memory formation and dysregulation of bdnf has been implicated in the …

Understanding the cellular and molecular mechanisms underlying the formation and
maintenance of memories is a central goal of the neuroscience community. It is well …

The formation of long-term memory involves a series of molecular and cellular changes,
including gene transcription, protein synthesis and synaptic plasticity dynamics. Some of …

Although the term 'epigenetics 'was coined nearly seventy years ago, its critical function in
memory processing by the adult CNS has only recently been appreciated. The hypothesis …

Although long-lasting behavioral memories have long been thought to require equally
persistent molecular changes, little is known about the biochemical underpinnings of …

Recent advances in chromatin biology have identified a role for epigenetic mechanisms in
the regulation of neuronal gene expression changes, a necessary process for proper …