[HTML][HTML] Safety assessment of conventional and biological systemic therapy in older adults with psoriasis, a real-world multicentre cohort study

ELM Ter Haar, EE Ten Bruin… - Acta Dermato …, 2022 - ncbi.nlm.nih.gov
Optimal selection of systemic therapy in older adults with psoriasis can be challenging, due
to sparse evidence-based guidance. This multicentre retrospective study investigated the …

Safety of classic and biologic systemic therapies for the treatment of psoriasis in elderly: an observational study from national BIOBADADERM registry

C Medina, G Carretero, C Ferrandiz… - Journal of the …, 2015 - Wiley Online Library
Background Psoriasis patients over 65 years‐old (elderly) constitute a growing group,
underrepresented in clinical trials, and likely to be more prone to adverse events. Objective …

Effectiveness and safety of systemic therapy for psoriasis in older adults: a systematic review

MEC van Winden, LS van der Schoot… - JAMA …, 2020 - jamanetwork.com
Importance Treating older adults with psoriasis can be challenging owing to comorbidities,
concomitant medication use, and consequent safety risks. Although many studies focus on …

Drug survival, safety, and effectiveness of biologics in older patients with psoriasis: a comparison with younger patients—a BioCAPTURE registry study

ELM Ter Haar, SE Thomas, J van den Reek, ME Otero… - Drugs & Aging, 2022 - Springer
Background Psoriasis is a common inflammatory disease in any age group, but also in older
patients (≥ 65 years of age). Since older patients are often excluded from clinical trials …

The safety of systemic treatments that can be used for geriatric psoriasis patients: a review

JW Wong, JYM Koo - Dermatology Research and Practice, 2012 - Wiley Online Library
Background. Patients with moderate‐to‐severe psoriasis are often treated with systemic
immunosuppressant agents that decrease immune system function. For the elderly, these …

Sex differences in adverse events from systemic treatments for psoriasis: A decade of insights from the Swiss Psoriasis Registry (SDNTT)

F Verardi, LV Maul, K Borsky… - Journal of the …, 2024 - Wiley Online Library
Background Psoriasis is a disease that often requires prolonged systemic treatment. It is
important to determine the safety of available therapies. There is currently little insight into …

Adverse events associated with discontinuation of the biologics/classic systemic treatments for moderate‐to‐severe plaque psoriasis: data from the Spanish Biologics …

I Belinchón, JM Ramos, G Carretero… - Journal of the …, 2017 - Wiley Online Library
Background Little is known about the adverse events (AE s) that lead to suspension of
systemic treatments for psoriasis in clinical practice. Objective The study aimed to …

Risk of serious adverse events associated with biologic and nonbiologic psoriasis systemic therapy: patients ineligible vs eligible for randomized controlled trials

I Garcia-Doval, G Carretero, F Vanaclocha… - Archives of …, 2012 - jamanetwork.com
Objective To describe the use of systemic therapy for psoriasis (biologic and nonbiologic
[classic] drugs) in patients not adequately represented in randomized controlled trials …

Biologic treatment in elderly patients with psoriasis: a systematic review

VK Sandhu, A Ighani, P Fleming… - Journal of Cutaneous …, 2020 - journals.sagepub.com
With our aging population, an increasing number of psoriasis patients are classified as
elderly. However, psoriasis treatment in older adults can be challenging, given an increased …

Real‐world safety and efficacy of biologics in elderly patients with psoriasis: A multicenter observational study

C Ohata, H Anezaki, T Yanase, E Katayama… - The Journal of … - Wiley Online Library
Clinical trials of biologics have frequently excluded elderly patients, resulting in inadequate
data on their safety and efficacy. Additionally, evidence of their safety and efficacy remains …