Parkinson's disease is the most common neurodegenerative movement disorder. The motor
impairments of Parkinson's disease are caused by the loss of dopaminergic neurons in the …

Several lines of evidence suggest that phosphorylation of α-synuclein (α-syn) at S87 or
S129 may play an important role in regulating its aggregation, fibrillogenesis, Lewy body …

Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the
substantia nigra (SN) and the appearance of fibrillar aggregates of insoluble α-synuclein (α …

Abnormal accumulation of proteinaceous intraneuronal inclusions called Lewy bodies (LBs)
is the neurpathological hallmark of Parkinson's disease (PD) and related synucleinopathies …

Parkinson's disease (PD) is a common neurodegenerative disease which usually associates
with neuroinflammation. The main pathological characteristics of PD are dopaminergic …

α-Synuclein (α-syn) phosphorylation at serine 129 (pS129–α-syn) is substantially increased
in Lewy body disease, such as Parkinson's disease (PD) and dementia with Lewy bodies …

A better understanding of the molecular and cellular determinants that influence the
pathology of Parkinson's disease (PD) is essential for developing effective diagnostic …

α-Synuclein (α-syn) phosphorylation at serine 129 is characteristic of Parkinson disease
(PD) and related α-synulceinopathies. However, whether phosphorylation promotes or …

Studies have shown that α-synuclein (α-syn) deposited in Lewy bodies in brain tissue from
patients with Parkinson disease (PD) is extensively phosphorylated at Ser-129. We used …

The aggregation of alpha synuclein (α‐syn) is a neuropathological feature that defines a
spectrum of disorders collectively termed synucleinopathies, and of these, Parkinson's …