Gene editing for advanced therapies: Governance, policy and society

H Garden, D Winickoff - 2018 - oecd-ilibrary.org
Gene editing aims to modify the genetic sequence at a precise genomic location. Recent
breakthroughs in gene editing techniques such as the clustered regularly interspaced short …

Gene editing for treatment and prevention of human diseases: a global survey of gene editing-related researchers

LFM Rocha, LAM Braga, FB Mota - Human Gene Therapy, 2020 - liebertpub.com
In the next decades, gene editing technologies are expected to be used in the treatment and
prevention of human diseases. Yet, the future uses of gene editing in medicine are still …

From fiction to science: clinical potentials and regulatory considerations of gene editing

M Schacker, D Seimetz - Clinical and translational medicine, 2019 - Springer
Gene editing technologies such as CRISPR/Cas9 have emerged as an attractive tool not
only for scientific research but also for the development of medicinal products. Their ability to …

Genomic editing: From human health to the “perfect child”

D Iancu - Clinical Ethics At the Crossroads of Genetic and …, 2023 - Elsevier
Since its discovery, CRISPR/Cas9 genome editing technique rapidly evolved from a
laboratory-restricted tool for biological research to a valid candidate for curative therapy of …

Genome-editing technologies: concept, pros, and cons of various genome-editing techniques and bioethical concerns for clinical application

SH Khan - Molecular Therapy-Nucleic Acids, 2019 - cell.com
The traditional healthcare system is at the doorstep for entering into the arena of molecular
medicine. The enormous knowledge and ongoing research have now been able to …

[PDF][PDF] A new era of gene editing for the treatment of human diseases

KC Mandip, CJ Steer - Swiss medical weekly, 2019 - smw.ch
The treatment of human diseases using gene-editing technology has been envisioned for
several decades with the realisation that so many were associated with mutations in DNA …

Gene editing and its applications in biomedicine

G Li, X Li, S Zhuang, L Wang, Y Zhu, Y Chen… - Science China Life …, 2022 - Springer
The steady progress in genome editing, especially genome editing based on the use of
clustered regularly interspaced short palindromic repeats (CRISPR) and programmable …

Current landscape of gene‐editing technology in biomedicine: Applications, advantages, challenges, and perspectives

W Zhou, J Yang, Y Zhang, X Hu, W Wang - MedComm, 2022 - Wiley Online Library
The expanding genome editing toolbox has revolutionized life science research ranging
from the bench to the bedside. These “molecular scissors” have offered us unprecedented …

The promise of gene editing: so close and yet so perilously far

DJ Segal - Frontiers in Genome Editing, 2022 - frontiersin.org
On the one hand, it is striking how the promise of genome editing is advancing. Regulatory
restrictions have largely eased on genetically engineered crops that carry genome …

Gene editing in clinical practice: where are we?

RD Mittal - Indian Journal of Clinical Biochemistry, 2019 - Springer
Multitude of gene-altering capabilities in combination with ease of design and low cost have
all led to the adoption of the sophisticated and yet simple gene editing system that are …