Discovering common pathogenetic processes between COVID-19 and sepsis by bioinformatics and system biology approach

L Lu, LP Liu, R Gui, H Dong, YR Su, XH Zhou… - Frontiers in …, 2022 - frontiersin.org
Corona Virus Disease 2019 (COVID-19), an acute respiratory infectious disease caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread rapidly …

Identification of key signaling pathways induced by SARS-CoV2 that underlie thrombosis and vascular injury in COVID-19 patients

AJ Maxwell, J Ding, Y You, Z Dong… - Journal of Leucocyte …, 2021 - academic.oup.com
The SARS-CoV-2 pandemic has led to hundreds of thousands of deaths and billions of
dollars in economic damage. The immune response elicited from this virus is poorly …

[HTML][HTML] Transcriptomic signatures and repurposing drugs for COVID-19 patients: findings of bioinformatics analyses

G Li, S Ruan, X Zhao, Q Liu, Y Dou, F Mao - Computational and Structural …, 2021 - Elsevier
The novel coronavirus SARS-CoV-2 is damaging the world's social and economic fabrics
seriously. Effective drugs are urgently needed to decrease the high mortality rate of COVID …

The use of bioinformatics methods to identify the effects of SARS-CoV-2 and influenza viruses on the regulation of gene expression in patients

Z Sun, L Ke, Q Zhao, J Qu, Y Hu, H Gao… - Frontiers in …, 2023 - frontiersin.org
Background SARS-CoV-2 infection is a respiratory infectious disease similar to influenza
virus infection. Numerous studies have reported similarities and differences in the clinical …

Bioinformatics and system biology approach to identify the influences of COVID-19 on rheumatoid arthritis

H Hu, N Tang, F Zhang, L Li, L Li - Frontiers in Immunology, 2022 - frontiersin.org
Background Severe coronavirus disease 2019 (COVID-19) has led to a rapid increase in
mortality worldwide. Rheumatoid arthritis (RA) was a high-risk factor for severe acute …

Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions

Z Nain, SK Barman, MM Sheam, SB Syed… - Briefings in …, 2021 - academic.oup.com
Despite the association of prevalent health conditions with coronavirus disease 2019
(COVID-19) severity, the disease-modifying biomolecules and their pathogenetic …

SARS‐CoV‐2 cellular tropism and direct multiorgan failure in COVID‐19 patients: Bioinformatic predictions, experimental observations, and open questions

AA Valyaeva, AA Zharikova… - Cell Biology …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus that causes
coronavirus disease 2019 (COVID‐19), has led to an unprecedented public health …

Identification of common dysregulated genes in COVID-19 and hypersensitivity pneumonitis: A systems biology and machine learning approach

S Dasgupta, SS Das, S Patidar, V Kajaria… - Omics: A Journal of …, 2023 - liebertpub.com
A comprehensive knowledge on systems biology of severe acute respiratory syndrome
coronavirus 2 is crucial for differential diagnosis of COVID-19. Interestingly, the radiological …

Pathogenetic profiling of COVID-19 and SARS-like viruses

Z Nain, HK Rana, P Liò, SMS Islam… - Briefings in …, 2021 - academic.oup.com
Abstract The novel coronavirus (2019-nCoV) has recently emerged, causing COVID-19
outbreaks and significant societal/global disruption. Importantly, COVID-19 infection …

[HTML][HTML] In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis

R Tiwari, AR Mishra, F Mikaeloff, S Gupta… - Computational and …, 2020 - Elsevier
The emergence and continued spread of SARS-CoV-2 have resulted in a public health
emergency across the globe. The lack of knowledge on the precise mechanism of viral …