G protein-coupled receptors (GPCRs) can exist as dimers or as larger oligomeric clusters
that enable intercommunication between different receptor protomers within the same …

The functional importance of G protein-coupled receptor (GPCR) oligomerization remains
controversial. Although obligate dimers of class C GPCRs are well accepted, the …

Although highly controversial just a few years ago, the idea that G‐protein‐coupled
receptors (GPCRs) may undergo homo‐oligomerization or hetero‐oligomerization has …

G-protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors in the human genome that respond to a plethora of signals, including …

G Protein Coupled Receptors (GPCRs) represent the largest family of membrane proteins in
the human genome, are the targets of approximately 25% of all marketed pharmaceuticals …

G protein‐coupled receptor (GPCR) oligomers are promising targets for the design of new
highly selective therapeutics. GPCRs have historically been attractive drug targets for their …

The classical idea that G‐protein‐coupled receptors (GPCRs) function as monomeric
entities has been unsettled by the emerging concept of GPCR dimerization. Recent findings …

Although the G protein-coupled receptor (GPCR) oligomerization has been questioned
during the last decade, under some premises the existence of a supramolecular …

A wide range of techniques have been employed to examine the quaternary structure of G-
protein-coupled receptors (GPCRs). Although it is well established that homo-dimerisation is …

The critical involvement of GPCRs (G-protein-coupled receptors) in nearly all physiological
processes, and the presence of these receptors at the interface between the extracellular …