Osier MV, Pakstis AJ, Soodyall H, Comas D, Goldman D, Odunsi K, Okonofua F, Parnas J,
Schulz LO, Bertranpetit J, Bonne-Tamir B, Lu RB, Kidd JR, Kidd KK (2002) A global …

Variants of different Class I alcohol dehydrogenase (ADH) genes have been shown to be
associated with an effect that is protective against alcoholism. Previous work from our …

Osier et al.(2002) report that haplotyping of the alcohol dehydrogenase (ADH) gene cluster
at 4q21-23 showed unusually high values for Fst, an estimator of population differentiation …

Two of the three class I alcohol dehydrogenase (ADH) genes (ADH2 and ADH3) encode
known functional variants that act on alcohol with different efficiencies. Variants at both these …

The set of alcohol-metabolizing enzymes has considerable genetic and functional
complexity. The relationships between some alcohol dehydrogenase (ADH) and aldehyde …

The alcohol dehydrogenase (ADH) family of enzymes catalyzes the reversible oxidation of
alcohol to acetaldehyde. Seven ADH genes exist in a segment of∼ 370 kb on 4q21 …

Alcoholism is a multifactorial and polygenic disorder involving complex gene‐to‐gene and
gene‐to‐environment interactions. Alcohol metabolism is one of the biological determinants …

We have previously found that variation in alcohol metabolism in Europeans is linked to the
chromosome 4q region containing the ADH gene family. We have now typed 103 single …

Enzymes encoded by two gene families, alcohol dehydrogenase (ADH) and aldehyde
dehydrogenase (ALDH), mediate alcohol metabolism in humans. Allelic variants have been …

The data were based on meta-analysis of the published results for 131 populations and the
results of genotyping of samples from 37 additional populations, performed by the authors …