The efficacy of conventional ocular formulations is limited by poor corneal retention and
permeation, resulting in low ocular bioavailability. Mucoadhesive chitosan (CS) …

Efficient drug delivery to the ocular region is a challenging goal. Only a very small amount
(about l-3%) of the dosage actually penetrates through the cornea and reaches intraocular …

Many formulation strategies have been employed to improve ocular bioavailability of topical
eye drops. The aim of this study was to develop and evaluate a series of solid lipid …

In this study, chitosan nanoparticles (CH-NPs) were used to encapsulate antibacterial agent
levofloxacin for the treatment of ocular infection. The chitosan nanoparticles were prepared …

Ophthalmic nanosuspensions (ONS) have shown a potential for ophthalmic delivery over
the conventional ocular formulations. The objective of the study was to assess the effect of …

Drug delivery to ocular region is a challenging task. Only 1–2% of drug is available in eye for
therapeutic action, rest of the drug is drained out through nasolachrymal drainage system …

Improving the bioavailability of a drug at the ocular surface presents a profound challenge.
Due to ocular physiological barriers, conventional eye drops exhibit poor bioavailability of …

Our work tackles the combined advantages of both nanotechnology and the bioadhesive gel
properties which were utilized to design an ocular drug delivery system that is capable to …

Aim Norfloxacin (NFX) has low ocular bioavailability. The current work aimed to develop
NFX-loaded nanoparticle (NP)-laden hydrogels to improve the ocular potential of NFX …

Conjunctivitis is considered as a common infection of ocular surfaces. Eye drop is most
commonly used for treatment of conjunctivitis, but has some drawback like 95% drug …