[HTML][HTML] Monocytes and Macrophages in COVID-19

R Knoll, JL Schultze, J Schulte-Schrepping - Frontiers in immunology, 2021 - frontiersin.org
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …

Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …

Monocytes and macrophages in COVID-19: Friends and foes

S Meidaninikjeh, N Sabouni, HZ Marzouni, S Bengar… - Life sciences, 2021 - Elsevier
The COVID-19 is a novel infectious disease caused by SARS-CoV-2 and is known as a
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …

Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis

A Boumaza, L Gay, S Mezouar, E Bestion… - The Journal of …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …

[PDF][PDF] Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes

N Liu, C Jiang, P Cai, Z Shen, W Sun, H Xu, M Fang… - Cell Reports, 2021 - cell.com
The mortality risk of coronavirus disease 2019 (COVID-19) patients has been linked to the
cytokine storm caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis

A Boumaza, L Gay, S Mezouar, AB Diallo, M Michel… - BioRxiv, 2020 - biorxiv.org
To date, the Covid-19 pandemic affected more than 18 million individuals and caused more
than 690, 000 deaths. Its clinical expression is pleiomorphic and severity is related to age …

[HTML][HTML] Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
With the objective of linking early findings relating to the novel SARS-CoV-2 coronavirus
with potentially informative findings from prior research literature and to promote …

[HTML][HTML] Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

M Merad, JC Martin - Nature reviews immunology, 2020 - nature.com
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …

[PDF][PDF] Severe COVID-19 is marked by a dysregulated myeloid cell compartment

J Schulte-Schrepping, N Reusch, D Paclik, K Baßler… - Cell, 2020 - cell.com
Summary Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract
infection, however, a subset of patients progress to severe disease and respiratory failure …