COVID-19: in the eye of the cytokine storm
R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …
Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19
S Mairpady Shambat, A Gomez-Mejia… - PLoS …, 2022 - journals.plos.org
COVID-19 displays diverse disease severities and symptoms including acute systemic
inflammation and hypercytokinemia, with subsequent dysregulation of immune cells …
inflammation and hypercytokinemia, with subsequent dysregulation of immune cells …
Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …
AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …
Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …
AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …
Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent
BACKGROUND Coronavirus disease 19 (COVID-19) is an emerging infectious disease
caused by SARS-CoV-2. Antiviral immune response is crucial to achieve pathogen …
caused by SARS-CoV-2. Antiviral immune response is crucial to achieve pathogen …
Single-cell transcriptome analysis highlights a role for neutrophils and inflammatory macrophages in the pathogenesis of severe COVID-19
Cumulative data link cytokine storms with coronavirus disease 2019 (COVID-19) severity.
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …
Severe COVID-19 recovery is associated with timely acquisition of a myeloid cell immune-regulatory phenotype
AC Trombetta, GB Farias, AMC Gomes… - Frontiers in …, 2021 - frontiersin.org
After more than one year since the COVID-19 outbreak, patients with severe disease still
constitute the bottleneck of the pandemic management. Aberrant inflammatory responses …
constitute the bottleneck of the pandemic management. Aberrant inflammatory responses …
[HTML][HTML] Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19
Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe
manifestations have largely been studied in circulation. Here, we examined the relationship …
manifestations have largely been studied in circulation. Here, we examined the relationship …
Immune responses in mildly versus critically ill COVID-19 patients
H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …
devastating effects on the global health and economic system. The cellular and molecular …