[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

Dysregulation of the immune response in coronavirus disease 2019

L Mohamed Khosroshahi, N Rezaei - Cell Biology International, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …

In the eye of the COVID-19 cytokine storm

N Vaninov - Nature Reviews Immunology, 2020 - nature.com
Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

Quantitative and qualitative alterations of circulating myeloid cells and plasmacytoid DC in SARS‐CoV‐2 infection

B Peruzzi, S Bencini, M Capone, A Mazzoni… - …, 2020 - Wiley Online Library
SARS‐CoV‐2 is responsible for a new infectious disease (COVID‐19) in which individuals
can either remain asymptomatic or progress from mild to severe clinical conditions including …

[HTML][HTML] COVID-19 severity associates with pulmonary redistribution of CD1c+ DCs and inflammatory transitional and nonclassical monocytes

I Sánchez-Cerrillo, P Landete, B Aldave… - The Journal of …, 2020 - Am Soc Clin Investig
SARS-CoV-2 is responsible for the development of coronavirus disease 2019 (COVID-19) in
infected individuals, who can either exhibit mild symptoms or progress toward a life …

[HTML][HTML] Myeloid-derived suppressor cells as a potential biomarker and therapeutic target in COVID-19

M Rowlands, F Segal, D Hartl - Frontiers in immunology, 2021 - frontiersin.org
Clinical presentations of COVID-19 are highly variable, yet the precise mechanisms that
govern the pathophysiology of different disease courses remain poorly defined. Across the …

Respiratory and systemic monocytes, dendritic cells, and myeloid‐derived suppressor cells in COVID‐19: Implications for disease severity

S Falck‐Jones, B Österberg… - Journal of Internal …, 2023 - Wiley Online Library
Since the beginning of the SARS‐CoV‐2 pandemic in 2020, researchers worldwide have
made efforts to understand the mechanisms behind the varying range of COVID‐19 disease …

[HTML][HTML] Heightened circulating interferon-inducible chemokines, and activated pro-cytolytic Th1-cell phenotype features covid-19 aggravation in the second week of …

C Tincati, ES Cannizzo, M Giacomelli… - Frontiers in …, 2020 - frontiersin.org
Covid-19 features a delayed onset of critical illness occurring approximately one week from
the beginning of symptoms, which corresponds to the bridging of innate and adaptive …

Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm

PA Mudd, JC Crawford, JS Turner, A Souquette… - Science …, 2020 - science.org
We pursued a study of immune responses in coronavirus disease 2019 (COVID-19) and
influenza patients. Compared to patients with influenza, patients with COVID-19 exhibited …

[HTML][HTML] Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states

LF Schimke, AHC Marques, GC Baiocchi… - Cells, 2022 - mdpi.com
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …