Mucosal vaccines—fortifying the frontiers

EC Lavelle, RW Ward - Nature Reviews Immunology, 2022 - nature.com
Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …

Mucosal vaccines: Strategies and challenges

M Li, Y Wang, Y Sun, H Cui, SJ Zhu, HJ Qiu - Immunology letters, 2020 - Elsevier
Mucosal immunization has potential benefits over conventional parenteral immunization,
eliciting immune defense in both mucosal and systemic tissue for protecting from pathogen …

Mucosal vaccines: a paradigm shift in the development of mucosal adjuvants and delivery vehicles

A Srivastava, DV Gowda, SRV Madhunapantula… - Apmis, 2015 - Wiley Online Library
Mucosal immune responses are the first‐line defensive mechanisms against a variety of
infections. Therefore, immunizations of mucosal surfaces from which majority of infectious …

Defending the mucosa: adjuvant and carrier formulations for mucosal immunity

LB Lawson, EB Norton, JD Clements - Current opinion in immunology, 2011 - Elsevier
A majority of infectious microorganisms either colonize or cross mucosal surfaces to enter
the host. A major goal in vaccine design is to induce a protective, lasting immune response …

Novel vaccine development strategies for inducing mucosal immunity

Y Fukuyama, D Tokuhara, K Kataoka… - Expert review of …, 2012 - Taylor & Francis
To develop protective immune responses against mucosal pathogens, the delivery route
and adjuvants for vaccination are important. The host, however, strives to maintain mucosal …

New insights in mucosal vaccine development

V Pavot, N Rochereau, C Genin, B Verrier, S Paul - Vaccine, 2012 - Elsevier
Mucosal surfaces are the major entrance for infectious pathogens and therefore mucosal
immune responses serve as a first line of defence. Most current immunization procedures …

Vaccines, adjuvants and key factors for mucosal immune response

VA Correa, AI Portilho, E De Gaspari - Immunology, 2022 - Wiley Online Library
Vaccines are the most effective tool to control infectious diseases, which provoke significant
morbidity and mortality rates. Most vaccines are administered through the parenteral route …

The development of mucosal vaccines for both mucosal and systemic immune induction and the roles played by adjuvants

SH Kim, YS Jang - Clinical and experimental vaccine …, 2017 - synapse.koreamed.org
Vaccination is the most successful immunological practice that improves the quality of
human life and health. Vaccine materials include antigens of pathogens and adjuvants …

Recent advances in mucosal vaccine development

H Chen - Journal of controlled release, 2000 - Elsevier
Proper stimulation of the mucosal immune system is critical for the effective protection of
mucosal surfaces against colonization and invasion of infectious agents. This requires …

Mucosal immunisation: adjuvants and delivery systems

PM Moyle, RP McGeary, JT Blanchfield… - Current Drug …, 2004 - ingentaconnect.com
The mucosal administration of vaccines is an area currently receiving a high level of interest
due to potential advantages offered by this technique. These advantages include the ability …