Genomic discovery and characterization of risk loci for type 2 diabetes (T2D) have been
conducted primarily in individuals of European ancestry. We conducted a multiethnic …

Abstract Purpose of Review Type 2 diabetes (T2D) is a multifactorial, heritable syndrome
characterized by dysregulated glucose homeostasis that results from impaired insulin …

Abstract Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic
and environmental risk factors that disproportionately afflicts communities of color …

The prevalence of type 2 diabetes (T2D) is greater in populations of African descent
compared to European-descent populations. Genetic risk factors may underlie the disparity …

To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale
meta-analyses by using a custom∼ 50,000 SNP genotyping array (the ITMAT-Broad-CARe …

Hispanic/Latino (HL) populations bear a disproportionately high burden of type 2 diabetes
(T2D). The ability to predict T2D genetic risk using polygenic risk scores (PRS) offers great …

Over 75 genetic loci within and outside of the HLA region influence type 1 diabetes risk.
Genetic risk scores (GRS), which facilitate the integration of complex genetic information …

Common genetic risk variants for type 2 diabetes (T2D) have primarily been identified in
populations of European and Asian ancestry. We tested whether the direction of association …

It has been recently hypothesized that many of the signals detected in genome-wide
association studies (GWAS) to T2D and other diseases, despite being observed to common …

Abstract Type 2 diabetes (T2D) is up to twice as prevalent among African Americans as
Caucasians. Recent genome-wide association studies (GWAS) have identified multiple …