G protein-coupled receptors (GPCR) comprise a diverse superfamily of over 800 proteins
that have gained relevance as biological targets for pharmaceutical drug design. Although …

G-protein-coupled receptors (GPCRs) constitute a large family of structurally similar proteins
that respond to a chemically diverse array of physiological and environmental stimulants …

During the past few years, crystallography of G protein–coupled receptors (GPCRs) has
experienced exponential growth, resulting in the determination of the structures of 16 distinct …

A number of recent technical solutions have led to significant advances in G protein-coupled
receptor (GPCR) structural biology. Apart from a detailed mechanistic view of receptor …

G protein–coupled receptors (GPCRs) are versatile molecular machines that regulate the
majority of physiological responses to chemically diverse hormones and neurotransmitters …

Crucial as molecular sensors for many vital physiological processes, seven-transmembrane
domain G protein-coupled receptors (GPCRs) comprise the largest family of proteins …

G protein-coupled receptors (GPCRs) represent the family of proteins with the highest
impact from social, therapeutic and economic point of view. Today, more than 50% of drug …

G protein–coupled receptor (GPCR) structural biology has progressed dramatically in the
last decade. There are now over 120 GPCR crystal structures deposited in the Protein Data …

As one of the most successful therapeutic target families, G protein-coupled receptors
(GPCRs) have experienced a transformation from random ligand screening to knowledge …

G protein-coupled receptors (GPCRs) are targeted by∼ 30–40% of marketed drugs, and
their key roles in normal physiology and in disease demonstrate that an understanding of …