SANS and Cryo-TEM study of self-assembled diblock copolypeptide hydrogels with rich nano-through microscale morphology

DJ Pochan, L Pakstis, B Ozbas, AP Nowak… - …, 2002 - ACS Publications
Hydrogels for superabsorption, drug delivery matrices, and tissue engineering scaffolds
have been traditionally constructed with high molecular weight, hydrophilic polymers that …

Tunable hydrogel morphology via self-assembly of amphiphilic pentablock copolypeptides

Z Li, TJ Deming - Soft Matter, 2010 - pubs.rsc.org
Hydrogels assembled from symmetric amphiphilic pentablock copolypeptides were
investigated using rheology and cryogenic transmission electron microscopy (cryoTEM) …

Self-sorting microscale compartmentalized block copolypeptide hydrogels

Y Sun, LA Bentolila, TJ Deming - ACS Macro Letters, 2019 - ACS Publications
Multicomponent interpenetrating network hydrogels possessing enhanced mechanical
stiffness compared to their individual components were prepared via physical mixing of …

Block Sequence Effects on the Self-Assembly Behaviors of Polypeptide-Based Penta-Block Copolymer Hydrogels

KH Wang, CH Liu, DH Tan, MP Nieh… - ACS Applied Materials & …, 2024 - ACS Publications
Peptide-based hydrogels have great potential for applications in tissue engineering, drug
delivery, and so on. We systematically synthesize, characterize, and investigate the self …

Structure and mechanical response of protein hydrogels reinforced by block copolymer self-assembly

MJ Glassman, BD Olsen - Soft Matter, 2013 - pubs.rsc.org
A strategy for responsively toughening an injectable protein hydrogel has been
implemented by incorporating an associative protein as the midblock in triblock copolymers …

Effect of chemistry and morphology on the biofunctionality of self-assembling diblock copolypeptide hydrogels

LM Pakstis, B Ozbas, KD Hales, AP Nowak… - …, 2004 - ACS Publications
Amphiphilic, diblock copolypeptides of hydrophilic lysine or glutamic acid and hydrophobic
leucine or valine have been observed to self-assemble into rigid hydrogels in aqueous …

Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles

AP Nowak, V Breedveld, L Pakstis, B Ozbas, DJ Pine… - Nature, 2002 - nature.com
Protein-based hydrogels are used for many applications, ranging from food and cosmetic
thickeners to support matrices for drug delivery and tissue replacement,,. These materials …

Recent trends in pH/thermo-responsive self-assembling hydrogels: from polyions to peptide-based polymeric gelators

C Chassenieux, C Tsitsilianis - Soft Matter, 2016 - pubs.rsc.org
In this article, we highlight some recent developments in “smart” physical hydrogels
achieved by self-assembling of block type macromolecules. More precisely we focus on two …

End groups adjusting the molecular nano-assembly pattern and thermal gelation of polypeptide block copolymer aqueous solution

JY Kim, MH Park, MK Joo, SY Lee, B Jeong - Macromolecules, 2009 - ACS Publications
We are reporting end-capping of the amino groups of a polypeptide block copolymer by
hydrophobic alkyl groups including methyl, ethyl, and propyl group. The end-capped …

Responsive organogels formed by supramolecular self assembly of PEG-block-allyl-functionalized racemic polypeptides into β-sheet-driven polymeric ribbons

J Zou, F Zhang, Y Chen, JE Raymond, S Zhang, J Fan… - Soft Matter, 2013 - pubs.rsc.org
A chemically reactive hybrid diblock polypeptide gelator poly (ethylene glycol)-block-poly
(DL-allylglycine)(PEG-b-PDLAG) is an exceptional material, due to the characteristics of …