The synthesis and evaluation of antiplasmodial activity of benzothiazole, benzimidazole,
benzoxazole and pyridine analogues of amodiaquine is hereby reported. Benzothiazole and …

Fluoroquinolone analogs were synthesized by simple alkylation followed by click chemistry
and evaluated for their antimalarial in vitro against chloroquine sensitive strain of …

In continuance with earlier reported work, an extension has been carried out by the same
research group. Mulling over the ongoing condition of resistance to existing antimalarial …

Malaria is endemic in tropical and subtropical regions of Africa, Asia, and the Americas. The
increasing prevalence of multi-drug-resistant Plasmodium falciparum drives the ongoing …

Antimalarial agents structurally based on novel pharmacophores, synthesized by low-cost
synthetic procedures and characterized by low potential for developing resistance are …

Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is
unable to salvage pyrimidines and must rely on de novo biosynthesis for survival …

Malaria continues to be an important public health problem in the world. Nowadays, the
widespread parasite resistance to many drugs used in antimalarial therapy has made the …

Malaria is a major public health problem all over the world, particularly in tropical and
subtropical countries due to the development of resistance and most deadly infection is …

The continued proliferation of malaria throughout temperate and tropical regions of the world
has promoted a push for more efficacious treatments to combat the disease. Unfortunately …

A series of 2-phenyl quinoline-4-carboxylic acid derivatives related to brequinar, an inhibitor
of human dihydroorotate dehydrogenase (DHODH), has been prepared and evaluated as …