The placenta is crucial for fetal development, yet the impact of environmental stressors such
as arsenic exposure remains poorly understood. We apply single-cell RNA sequencing to …

Maternal stress during pregnancy exerts long-term effects on the mental well-being of the
offspring. However, the long-term effect of prenatal exposure on the offspring's mental status …

The placenta is a heterogeneous organ whose development involves complex interactions
of trophoblasts with decidual, vascular, and immune cells at the fetal–maternal interface. It …

Prenatal exposure to maternal psychological stress is associated with increased risk for
adverse birth and child health outcomes. Accumulating evidence suggests that …

Abstract According to the “Developmental Origins of Health and Disease”(DOHaD) concept,
the early-life environment is a critical period for fetal programming. Given the …

Introduction Murine models provide evidence that maternal stress during pregnancy can
influence placenta morphology and function, including altered expression of genes involved …

Prenatal exposure to air pollution is a significant risk factor for the mother and the
developing foetus. The accumulation of pollutants in the placenta can cause a self-cascade …

Background Sex-specific factors play a major role in human health and disease, including
responses to environmental stresses such as toxicant exposure. Increasing evidence …

Background Gestational exposure to ambient air pollution has been associated with adverse
health outcomes for mothers and newborns. The placenta is a central regulator of the in …

There is a growing interest in understanding the mechanisms that drive the developmental
origins of health and disease, and the role of epigenetic regulation has risen to the forefront …