As resident macrophages of the central nervous system (CNS), microglia are associated
with diverse functions essential to the developing and adult brain during homeostasis and …

Microglia are macrophages of the central nervous system (CNS) that continuously scrutinize
their environment for damage. They colonize the cephalic mesenchyme during …

Intercellular signaling molecules such as cytokines and their receptors enable immune cells
to communicate with one another and their surrounding microenvironments. Emerging …

Macrophages are major cell types of the immune system, and they comprise both tissue‐
resident populations and circulating monocyte‐derived subsets. Here, we discuss microglia …

Microglia, the tissue-resident macrophages of the central nervous system (CNS), have
characterized roles in combating infection, clearing cellular debris, and maintaining tissue …

Microglia—resident myeloid-lineage cells in the brain and the spinal cord parenchyma—
function in the maintenance of normal tissue homeostasis. Microglia also act as sentinels of …

Inflammation is a hallmark of different central nervous system (CNS) pathologies. It has been
linked to neurodegenerative disorders as well as primary and metastatic brain tumors …

The immune system of the central nervous system (CNS) consists primarily of innate
immune cells. These are highly specialized macrophages found either in the parenchyma …

Microglia are resident cells of the brain that regulate brain development, maintenance of
neuronal networks, and injury repair. Microglia serve as brain macrophages but are distinct …

Originally hypothesized to function solely as immunologic responders within the central
nervous system (CNS), emerging evidence has revealed that microglia have more complex …