Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses

BL Sievers, S Chakraborty, Y Xue, T Gelbart… - Science translational …, 2022 - science.org
Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that have
mutations associated with increased transmission and antibody escape have arisen over the …

Fractionating a COVID-19 Ad5-vectored vaccine improves virus-specific immunity

S Sanchez, N Palacio, T Dangi, T Ciucci… - Science …, 2021 - science.org
SARS-CoV-2 has caused a global pandemic that has infected more than 250 million people
worldwide. Although several vaccine candidates have received emergency use …

[HTML][HTML] A booster dose of Delta× Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants

IJ Lee, CP Sun, PY Wu, YH Lan, IH Wang… - Journal of biomedical …, 2022 - Springer
Background With the continuous emergence of new SARS-CoV-2 variants that feature
increased transmission and immune escape, there is an urgent demand for a better vaccine …

[HTML][HTML] Boosting with updated COVID-19 mRNA vaccines

D Bhattacharya, GD Victora - nature medicine, 2022 - nature.com
Boosting with updated COVID-19 mRNA vaccines | Nature Medicine Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for …

A valid protective immune response elicited in rhesus macaques by an inactivated vaccine is capable of defending against SARS-CoV-2 infection

H Chen, Z Xie, R Long, S Fan, H Li, Z He, K Xu, Y Liao… - bioRxiv, 2020 - biorxiv.org
With the relatively serious global epidemic outbreak of SARS-CoV-2 infection, public
concerns focus on not only clinical therapeutic measures and public quarantine for this …

[HTML][HTML] Heterologous prime-boost immunizations with chimpanzee adenoviral vectors elicit potent and protective immunity against SARS-CoV-2 infection

J Liu, K Xu, M Xing, Y Zhuo, J Guo, M Du, Q Wang… - Cell Discovery, 2021 - nature.com
A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is urgently needed to tackle the COVID-19 global pandemic. Here, we describe the …

[HTML][HTML] Optimised non-coding regions of mRNA SARS-CoV-2 vaccine CV2CoV improves homologous and heterologous neutralising antibody responses

N Roth, J Schön, D Hoffmann, M Thran, A Thess… - Vaccines, 2022 - mdpi.com
More than two years after the emergence of SARS-CoV-2, 33 COVID-19 vaccines, based on
different platforms, have been approved in 197 countries. Novel variants that are less …

High genetic barrier to escape from human polyclonal SARS-CoV-2 neutralizing antibodies

F Schmidt, Y Weisblum, M Rutkowska, D Poston… - bioRxiv, 2021 - biorxiv.org
The number and variability of the neutralizing epitopes targeted by polyclonal antibodies in
SARS-CoV-2 convalescent and vaccinated individuals are key determinants of …

[HTML][HTML] Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA. 5 Omicron variant in mice

SM Scheaffer, D Lee, B Whitener, B Ying, K Wu… - Nature medicine, 2023 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …

[HTML][HTML] Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques

C Shan, YF Yao, XL Yang, YW Zhou, G Gao, Y Peng… - Cell research, 2020 - nature.com
The 2019 novel coronavirus (SARS-CoV-2) outbreak is a major challenge for public health.
SARS-CoV-2 infection in human has a broad clinical spectrum ranging from mild to severe …