mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection

L Stamatatos, J Czartoski, YH Wan, LJ Homad, V Rubin… - Science, 2021 - science.org
Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have
raised concerns about resistance to neutralizing antibodies elicited by previous infection or …

[HTML][HTML] Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

Y Sui, J Li, R Zhang, SK Prabhu, H Andersen… - JCI insight, 2021 - ncbi.nlm.nih.gov
Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have
focused on systemic immunization, here we compared the protective efficacy of 2 …

Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B. 1.1. 7 (Alpha) and B. 1.351 (Beta)

J Trimpert, JM Adler, K Eschke, A Abdelgawad… - Science …, 2021 - science.org
Vaccines are instrumental and indispensable in the fight against the COVID-19 pandemic.
Several recent SARS-CoV-2 variants are more transmissible and evade infection-or vaccine …

Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral …

DW Hawman, K Meade-White, C Clancy, J Archer… - …, 2022 - thelancet.com
Background In late 2021, the SARS-CoV-2 Omicron (B. 1.1. 529) variant of concern (VoC)
was reported with many mutations in the viral spike protein that were predicted to enhance …

[HTML][HTML] COVID-19 vaccines: modes of immune activation and future challenges

JR Teijaro, DL Farber - Nature Reviews Immunology, 2021 - nature.com
The new vaccines against SARS-CoV-2 are novel in terms of specificity, their wide
dissemination across the global population and the inclusion of newly licensed mRNA …

Innate immune responses to SARS-CoV-2 in infected and vaccinated individuals

NK Saksena, PA Reche, SR Bonam… - Frontiers in …, 2023 - frontiersin.org
The COVID-19 pandemic triggered the intensity of the pursuit of vaccines that had not been
seen before and were developed at an unprecedented speed, approved, and delivered for …

Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later

EC Milligan, K Olstad, CA Williams, M Mallory… - Science Translational …, 2022 - science.org
The US Food and Drug Administration only gave emergency use authorization of the
BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines for infants 6 months and older in June …

mRNA vaccine-induced antibodies more effective than natural immunity in neutralizing SARS-CoV-2 and its high affinity variants

Y Yu, D Esposito, Z Kang, J Lu, AT Remaley… - Scientific Reports, 2022 - nature.com
Several variants of SARS-CoV-2 have emerged. Those with mutations in the angiotensin-
converting enzyme (ACE2) receptor binding domain (RBD) are associated with increased …

Differential neutralization and inhibition of SARS-CoV-2 variants by antibodies elicited by COVID-19 mRNA vaccines

L Wang, MH Kainulainen, N Jiang, H Di… - Nature …, 2022 - nature.com
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
resulted in the emergence of new variant lineages that have exacerbated the COVID-19 …

Effectiveness of a broad-spectrum bivalent mRNA vaccine against SARS-CoV-2 variants in preclinical studies

J Lu, S Tan, H Gu, K Liu, W Huang, Z Yu… - Emerging Microbes & …, 2024 - Taylor & Francis
Vaccines utilizing modified messenger RNA (mRNA) technology have shown robust
protective efficacy against SARS-CoV-2 in humans. As the virus continues to evolve in both …