[HTML][HTML] Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice
K Wu, A Choi, M Koch, S Elbashir, LZ Ma, D Lee… - Vaccine, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of a
global pandemic. Safe and effective COVID-19 vaccines are now available, including mRNA …
global pandemic. Safe and effective COVID-19 vaccines are now available, including mRNA …
A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2
Q Huang, K Ji, S Tian, F Wang, B Huang, Z Tong… - Nature …, 2021 - nature.com
The rapid expansion of the COVID-19 pandemic has made the development of a SARS-CoV-
2 vaccine a global health and economic priority. Taking advantage of versatility and rapid …
2 vaccine a global health and economic priority. Taking advantage of versatility and rapid …
SARS-CoV-2 mRNA vaccines: immunological mechanism and beyond
To successfully protect against pathogen infection, a vaccine must elicit efficient adaptive
immunity, including B and T cell responses. While B cell responses are key, as they can …
immunity, including B and T cell responses. While B cell responses are key, as they can …
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
WF Garcia-Beltran, KJS Denis, A Hoelzemer, EC Lam… - Cell, 2022 - cell.com
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.
1/B. 1.1. 529) harboring up to 36 mutations in spike protein, the target of neutralizing …
1/B. 1.1. 529) harboring up to 36 mutations in spike protein, the target of neutralizing …
A capsid virus-like particle-based SARS-CoV-2 vaccine induces high levels of antibodies and protects rhesus macaques
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide
pandemic. Here, we present non-human primate immunogenicity and protective efficacy …
pandemic. Here, we present non-human primate immunogenicity and protective efficacy …
Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+ Protein co-immunization in rhesus macaques
M Rosati, M Agarwal, X Hu, S Devasundaram… - PLoS …, 2021 - journals.plos.org
The speed of development, versatility and efficacy of mRNA-based vaccines have been
amply demonstrated in the case of SARS-CoV-2. DNA vaccines represent an important …
amply demonstrated in the case of SARS-CoV-2. DNA vaccines represent an important …
RBD-mRNA vaccine induces broadly neutralizing antibodies against Omicron and multiple other variants and protects mice from SARS-CoV-2 challenge
Multiple SARS-CoV-2 variants are identified with higher rates of transmissibility or greater
disease severity. Particularly, recent emergence of Omicron variant with rapid human-to …
disease severity. Particularly, recent emergence of Omicron variant with rapid human-to …
mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern
INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA
vaccines are highly effective at preventing infection and especially severe disease …
vaccines are highly effective at preventing infection and especially severe disease …
Protection against SARS-CoV-2 Beta variant in mRNA-1273 vaccine–boosted nonhuman primates
KS Corbett, M Gagne, DA Wagner, S O'Connell… - Science, 2021 - science.org
Neutralizing antibody responses gradually wane against several variants of concern (VOCs)
after vaccination with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
after vaccination with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines
Despite the successes of current coronavirus disease 2019 (COVID-19) vaccines, waning
immunity, the emergence of variants of concern, and breakthrough infections among …
immunity, the emergence of variants of concern, and breakthrough infections among …