Low polydispersity, low molecular weight biotechnological chondroitin sulfate with anti-inflammatory and antiarthritis activity and use thereof in the prevention of …

P Bazza, D Bianchi, N Miraglia, M Valetti… - US Patent …, 2020 - Google Patents
Disclosed is a low molecular weight (1000-5000 daltons) chondroitin sulfate (CS) produced
by chemical sulfation of a non-sulfated chondroitin backbone (K4 capsular polysaccharide) …

Low-molecular-weight biotechnological chondroitin 6-sulphate for prevention of osteoarthritis

N Miraglia, D Bianchi, E Valoti, A Trentin… - US Patent App. 14 …, 2015 - Google Patents
Disclosed is a low-molecular-weight (1000-5000 daltons) chondroitin sulphate (CS)
produced by chemical sulphation and subsequent depolymerisation of a non-sulphated …

Low-Molecular-Weight Biotechnological Chondroitin 6-Sulphate for Prevention of Osteoarthritis

N Miraglia, D Bianchi, E Valoti, A Trentin… - US Patent App. 14 …, 2016 - Google Patents
Disclosed is a low-molecular-weight (1000-5000 daltons) chondroitin sulphate (CS)
produced by chemical sulphation and Subsequent depolymerisation of a non-Sulphated …

Biotechnological sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof

D Bianchi, M Valetti, P Bazza, N Miraglia… - US Patent …, 2017 - Google Patents
(57) ABSTRACT A process for the preparation of a chondroitin Sulphate salt with an average
molecular weight (Mw) of 10-30 kDa via chemical Sulphation of an unsulphated chondroitin …

Biotechnological sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof

D Bianchi, M Valetti, P Bazza, N Miraglia… - US Patent App. 14 …, 2014 - Google Patents
The present invention discloses a process for the production of chondroitin sulphate with an
average molecular weight (Mw) of 10-30 kDa by chemical sulphation starting from an …

Biotechnological sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof

D Bianchi, M Valetti, P Bazza, N Miraglia… - US Patent …, 2018 - Google Patents
The present invention discloses a process for the production of chondroitin sulphate with an
average molecular weight (Mw) of 10-30 kDa by chemical sulphation starting from an …

Low molecular weight chondroitin sulfate, composition, preparation method and use thereof

H Zhang, S Chen, B Jin, Y Xu… - US Patent App. 18 …, 2023 - Google Patents
The invention relates to a low molecular weight sulfate chondroitin and a preparation
method thereof. A low molecular weight chondroitin sulfate with the average molecular …

Process for preparing CSA or CSC

PG Rucker - US Patent 4,302,577, 1981 - Google Patents
An improved process or method for the preparation of pharmaceutical grade biologically and
physiologically" active" chondroitin sulfate, predominantly chondroitin sulfate A, chondroitin …

Biotechnologica sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof

D Bianchi, M Valetti, P Bazza, N Miraglia, E Valoti - 2012 - air.unimi.it
The present invention disclosed a process for the production of chondroitin sulphated with
an average molecular weigh (Mw) of 10-30 KDa by chemical sulphation starting from an …

Process for the production of chondroitin polysulfate

K Nagasawa - US Patent 3,454,560, 1969 - Google Patents
Depolymerization and sulfation of chondroitin mono sulfate by sulfuric acid. Chondroitin
monosulfate is dis solved at a temperature of from-30 C. to--50 C. in a concentrated sulfuric …