Glial cells are traditionally regarded as elements for structural support and ionic
homeostasis, but have recently attracted attention as putative integral elements of the …

S100B is the major low-affinity Ca2+-binding protein in astrocytes. In order to study the role
of S100B in the maintenance of Ca2+ homeostasis, we generated S100B null mice by a …

The S100A4 protein belongs to the S100 family of vertebrate-specific proteins possessing
both intra-and extracellular functions. In the nervous system, high levels of S100A4 …

Using light and electron microscopic immunocytochemistry, we examined the expression of
the Ca2+-binding protein S100B in the dentate gyrus of adult rats during lesion-induced …

S100β is a calcium-binding protein elevated in Down's syndrome and Alzheimer's disease.
Previous studies have demonstrated that S100β is trophic for several neuronal populations …

Recent evidence suggests that slowly propagating Ca2+ waves from astrocytes can
modulate the function of neurons. Altering astrocytic calcium processes in vivo may therefore …

S100B is a small calcium-and zinc-binding protein expressed by astrocytes in the central
nervous system. Here, we examined the role of S100B in epileptogenesis using an …

The S100B protein belongs to the S100 family of EF-hand calcium binding proteins
implicated in cell growth and differentiation. Here, we show that in the developing and the …

S100B is the principal calcium-binding protein of astrocytes and known to be secreted to
extracellular space. Although secreted S100B has been reported to promote neurite …

1. S100B is a calcium-binding protein expressed and secreted by astrocytes, which has
been implicated in glial-neuronal communication. Extracellular S100B appears to protect …