Telomeres, the end fragments of chromosomes, play key roles in cellular proliferation and
senescence. Here we characterize the genetic architecture of naturally occurring variation in …

Leukocyte telomere length (LTL) is a proposed marker of biological age. Here we report the
measurement and initial characterization of LTL in 474,074 participants in UK Biobank. We …

Leukocyte telomere length (LTL), which reflects telomere length in other somatic tissues, is a
complex genetic trait. Eleven SNPs have been shown in genome-wide association studies …

Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer
and several age-associated diseases. We report here a genome-wide meta-analysis of …

Humans display a large inter-individual variation in leukocyte telomere length (LTL), which
is influenced by heredity, sex, race/ethnicity, paternal age at conception and environmental …

Epidemiological studies have principally relied on measurements of telomere length (TL) in
leucocytes, which reflects TL in other somatic cells. Leucocyte TL (LTL) displays vast …

Telomeres play a central role in cellular senescence and cancer pathobiology and are
associated with age-related diseases such as atherosclerosis and dementia. Telomere …

The average length of telomere repeats (TL) declines with age and is considered to be a
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …

Background Leucocyte telomere length (LTL) is a complex trait associated with ageing and
longevity. LTL dynamics are defined by LTL and its age-dependent attrition. Strong, but …

Genetic studies on telomere length are important for understanding age-related diseases.
Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here …