The clearance of surplus, broken, or dangerous components is key for maintaining cellular
homeostasis. The failure to remove protein aggregates, damaged organelles, or intracellular …

Selective autophagy ensures recognition and removal of various cytosolic cargos. Hence,
aggregated proteins, damaged organelles, or pathogens are enclosed into the double …

Selective autophagy is critical for regulating cellular homeostasis by mediating lysosomal
turnover of a wide variety of substrates including proteins, aggregates, organelles, and …

Autophagy is a highly conserved catabolic process cells use to maintain their homeostasis
by degrading misfolded, damaged and excessive proteins, nonfunctional organelles, foreign …

Autophagy is a catabolic pathway conserved among eukaryotes that allows cells to rapidly
eliminate large unwanted structures such as aberrant protein aggregates, superfluous or …

Autophagy is the catabolic process by which the cell degrades cytoplasmic components
within lysosomes. 1 The balance between the biosynthesis of cellular components and their …

Selective autophagy regulates the abundance of specific cellular components via a
specialized arsenal of factors, termed autophagy receptors, that target protein complexes …

Autophagy is an evolutionarily-conserved catabolic process initiated by the engulfment of
cytosolic components in a crescent-shaped structure, called the phagophore, that expands …

Cellular homeostasis requires the swift and specific removal of damaged material. Selective
autophagy represents a major pathway for the degradation of such cargo material. This is …

Autophagy is a lysosome-mediated degradative system that is a highly conserved pathway
present in all eukaryotes. In all cells, double-membrane autophagosomes form and engulf …