Autophagy is an evolutionarily conserved pathway, in which cytoplasmic components are
sequestered within double-membrane vesicles called autophagosomes and then …

Autophagy is traditionally depicted as a signaling cascade that culminates in the formation of
an autophagosome that degrades cellular cargo. However, recent studies have identified …

Macroautophagy/autophagy is an evolutionarily conserved cellular degradation process that
targets cytoplasmic materials including cytosol, macromolecules and unwanted organelles …

Autophagy is a highly conserved process that allows cells, tissues and organs to survive
onslaughts such as nutrient deprivation, inflammation, hypoxia and other stresses. The core …

Autophagy is the main cellular catabolic process responsible for degrading organelles and
large protein aggregates. It is initiated by the formation of a unique membrane structure, the …

Autophagy is a self‐eating system conserved among eukaryotes, in which cellular
components including organelles are entrapped into a double membrane structure called …

Ubiquitination, the post-translational modification essential for various intracellular
processes, is implicated in multiple aspects of autophagy, the major lysosome/vacuole …

Ubiquitination has long been recognised as a key determinator of protein fate by tagging
proteins for proteasomal degradation. Most recently, the ability of conjugated ubiquitin …

Autophagy is an evolutionarily conserved process whereby damaged and redundant
components of the cell are degraded in structures called autophagolysosomes. Currently …

Autophagy is an intracellular degradation pathway conserved in eukaryotes. Among core
autophagy-related (Atg) proteins, mammalian Atg9A is the sole multi-spanning …