Emerging strategies on in silico drug development against COVID-19: challenges and opportunities

M Yadav, S Dhagat, JS Eswari - European Journal of Pharmaceutical …, 2020 - Elsevier
The importance of coronaviruses as human pathogen has been highlighted by the recent
outbreak of SARS-CoV-2 leading to the search of suitable drugs to overcome respiratory …

In silico investigation and potential therapeutic approaches of natural products for COVID-19: Computer-aided drug design perspective

MM Rahman, MR Islam, S Akash, SA Mim… - Frontiers in Cellular …, 2022 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
substantial number of deaths around the world, making it a serious and pressing public …

Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus

CA Omolo, N Soni, VO Fasiku, I Mackraj… - European Journal of …, 2020 - Elsevier
The global pandemic of coronavirus disease 2019 (COVID-19), caused by novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in over 7,273,958 …

Deep Learning Approach for Discovery of In Silico Drugs for Combating COVID‐19

N Jha, D Prashar, M Rashid, M Shafiq… - Journal of healthcare …, 2021 - Wiley Online Library
Early diagnosis of pandemic diseases such as COVID‐19 can prove beneficial in dealing
with difficult situations and helping radiologists and other experts manage staffing more …

Molecular scaffolds from mother nature as possible lead compounds in drug design and discovery against coronaviruses: A landscape analysis of published literature …

A Khursheed, V Jain, A Rasool, MA Rather… - Microbial …, 2021 - Elsevier
The recent outbreak of viral infection and its transmission has highlighted the importance of
its slowdown for the safeguard of public health, globally. The identification of novel drugs …

Repurposing drugs for treatment of SARS-CoV-2 infection: computational design insights into mechanisms of action

S Kandwal, D Fayne - Journal of Biomolecular Structure and …, 2022 - Taylor & Francis
The COVID-19 pandemic has negatively affected human life globally. It has led to economic
crises and health emergencies across the world, spreading rapidly among the human …

In Silico Models for Anti‐COVID‐19 Drug Discovery: A Systematic Review

OH Onyango - Advances in pharmacological and …, 2023 - Wiley Online Library
The coronavirus disease 2019 (COVID‐19) is a severe worldwide pandemic. Due to the
emergence of various SARS‐CoV‐2 variants and the presence of only one Food and Drug …

Step toward repurposing drug discovery for COVID‐19 therapeutics through in silico approach

BN Marak, J Dowarah, L Khiangte… - Drug Development …, 2021 - Wiley Online Library
The outbreak of SARS‐CoV‐2 has become a threat to global health and has led to a global
economic crisis. Although the researchers worldwide are putting tremendous effort toward …

[HTML][HTML] Molecules against Covid-19: An in silico approach for drug development

R Bharti, SK Shukla - Journal of Electronic Science and Technology, 2021 - Elsevier
A large number of deaths have been caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) worldwide, turning it into a serious and momentous threat to …

Identifying and repurposing antiviral drugs against severe acute respiratory syndrome coronavirus 2 with in silico and in vitro approaches

K Watashi - Biochemical and Biophysical Research …, 2021 - Elsevier
Abstract Coronavirus infectious diseases 2019 (COVID-19), a global pandemic caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been a serious public …