Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn's disease

S Rajca, V Grondin, E Louis… - Inflammatory bowel …, 2014 - academic.oup.com
Background Crohn's disease (CD)–associated dysbiosis could predispose patients to
relapse. Gut microbiota composition of patients from the prospective cohort study designed …

Fecal microbiota signatures are associated with response to ustekinumab therapy among Crohn's disease patients

MK Doherty, T Ding, C Koumpouras, SE Telesco… - MBio, 2018 - Am Soc Microbiol
The fecal microbiota is a rich source of biomarkers that have previously been shown to be
predictive of numerous disease states. Less well studied is the effect of immunomodulatory …

Specificities of the intestinal microbiota in patients with inflammatory bowel disease and Clostridium difficile infection

H Sokol, S Jegou, C McQuitty, M Straub, V Leducq… - Gut …, 2018 - Taylor & Francis
Clostridium difficile infection (CDI) is a common complication in inflammatory bowel disease
(IBD) and has been associated with poor IBD outcome. Intestinal microbiota composition in …

Characteristics of faecal microbiota in paediatric Crohn's disease and their dynamic changes during infliximab therapy

Y Wang, X Gao, A Ghozlane, H Hu, X Li… - Journal of Crohn's …, 2018 - academic.oup.com
Background Crohn's disease [CD] is known to be associated with gut microbial dysbiosis.
Infliximab [IFX] is increasingly used to treat paediatric CD; however, it is not clear how the …

[HTML][HTML] Compositional changes in fecal microbiota associated with clinical phenotypes and prognosis in Korean patients with inflammatory bowel disease

SY Shin, Y Kim, WS Kim, JM Moon, KM Lee… - Intestinal …, 2023 - synapse.koreamed.org
Methods Fecal samples from 70 ulcerative colitis (UC) patients, 39 Crohn's disease (CD)
patients, and 100 healthy control individuals (HC) were collected. The fecal samples were …

Integration of taxa abundance and occurrence frequency to identify key gut bacteria correlated to clinics in Crohn's disease

X Cai, N Zhou, Q Zou, Y Peng, L Xu, L Feng, X Liu - BMC microbiology, 2023 - Springer
Bacteria abundance alternation in the feces or mucosa of Crohn's disease (CD) patients has
long been applied to identify potential biomarkers for this disease, while the taxa occurrence …

Alterations in gut microbial communities across anatomical locations in inflammatory bowel diseases

Y Zhou, Y He, L Liu, W Zhou, P Wang, H Hu… - Frontiers in …, 2021 - frontiersin.org
We previously discovered that gut microbiota can serve as universal microbial biomarkers
for diagnosis, disease activity assessment, and predicting the response to infliximab …

Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach

C Manichanh, L Rigottier-Gois, E Bonnaud, K Gloux… - Gut, 2006 - gut.bmj.com
Background and aim: A role for the intestinal microbial community (microbiota) in the onset
and chronicity of Crohn's disease (CD) is strongly suspected. However, investigation of such …

Diving into inflammation: a pilot study exploring the dynamics of the immune–microbiota axis in ileal tissue layers of patients with Crohn's disease

E Russo, F Giudici, F Ricci, S Scaringi… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims The pathogenesis of Crohn's disease [CD] is still unclear.
Disorders in the mucosal immunoregulation and its crosstalk with the microbiota may …

Determination of the discriminant score of intestinal microbiota as a biomarker of disease activity in patients with ulcerative colitis

K Fukuda, Y Fujita - BMC gastroenterology, 2014 - Springer
Background In recent years, the gut microbiota has been found to provide an important link
to the development of inflammatory bowel diseases (IBD) like ulcerative colitis (UC) …