COVID-19 spans a wide range of symptoms, sometimes with profound immune system
involvement. How immune cell subsets change during the disease course and with disease …

Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

Severe COVID-19 disease is associated with dysregulation of the myeloid compartment
during acute infection. Survivors frequently experience long-lasting sequelae, but little is …

The disease spectrum of coronavirus disease 2019 (COVID-19) ranges from no symptoms to
multisystem failure and death. Characterization of virus-specific immune responses to …

Neutrophils are recognized as important circulating effector cells in the pathophysiology of
severe coronavirus disease 2019 (COVID-19). However, their role within the inflamed lungs …

Ongoing observational clinical research has prioritized understanding the human immune
response to SARS-CoV-2 during the coronavirus disease 2019 (COVID-19) pandemic …

Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe
manifestations have largely been studied in circulation. Here, we examined the relationship …

While most COVID-19 patients have mild symptoms, about 15% of patients develop severe
COVID-19 often with fatal outcomes, and scientists have been on the hunt to understand the …

Summary Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract
infection, however, a subset of patients progress to severe disease and respiratory failure …

BACKGROUND. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
coronavirus 2 (SARS-CoV-2), has become a pandemic. This study addresses the clinical …