A comparison of model order reduction techniques for a four-dimensional population balance model describing multi-component wet granulation processes

D Barrasso, R Ramachandran - Chemical engineering science, 2012 - Elsevier
Three-dimensional (3-D) population balance equations are often used to model wet
granulation processes, simulating distributions in particle size, liquid binder content, and …

A three-dimensional population balance model of granulation with a mechanistic representation of the nucleation and aggregation phenomena

JMH Poon, CD Immanuel, FJ Doyle Iii… - Chemical Engineering …, 2008 - Elsevier
A comprehensive model is discussed for wet granulation based on a three-dimensional
population balance, as an attempt to capture particle-level phenomena and their influence …

An extended cell-average technique for a multi-dimensional population balance of granulation describing aggregation and breakage

A Chaudhury, A Kapadia, AV Prakash… - Advanced Powder …, 2013 - Elsevier
This paper focuses on obtaining the numerical solution to a three-dimensional population
balance model (PBM) of granulation using the cell-average technique first proposed by [22] …

Development of a multi-compartment population balance model for high-shear wet granulation with discrete element method

KF Lee, M Dosta, AD McGuire, S Mosbach… - Computers & chemical …, 2017 - Elsevier
This paper presents a multi-compartment population balance model for wet granulation
coupled with DEM (discrete element method) simulations. Methodologies are developed to …

A computationally efficient technique for the solution of multi-dimensional PBMs of granulation via tensor decomposition

A Chaudhury, I Oseledets, R Ramachandran - Computers & chemical …, 2014 - Elsevier
Multi-dimensional population balance equations (PBEs) are commonly used to describe the
dynamics of particulate processes such as granulation. Such a class of equations are …

Compartment based population balance modeling of a high shear wet granulation process using data analytics

A Chaudhury, ME Armenante… - … Research and Design, 2015 - Elsevier
Population balance models (PBMs) are used extensively to model various particulate
processes such as granulation. A high shear granulation process is often assumed to be …

Model order reduction of a multi-scale PBM-DEM description of a wet granulation process via ANN

D Barrasso, A Tamrakar, R Ramachandran - Procedia Engineering, 2015 - Elsevier
Wet granulation is a particle design process, often used in the pharmaceutical, consumer
product, food, and fertilizer industries. A better process understanding is needed to improve …

Modeling continuous high-shear wet granulation with DEM-PB

T Kulju, M Paavola, H Spittka, RL Keiski… - Chemical Engineering …, 2016 - Elsevier
A multiscale modeling procedure is introduced in this paper for modeling continuous high-
shear wet granulation. Flow inside the granulator is accounted using the discrete element …

Solution technique for a multi-dimensional population balance model describing granulation processes

CD Immanuel, FJ Doyle III - Powder Technology, 2005 - Elsevier
An efficient and novel solution technique is presented for solving multi-dimensional
population balance models. In addition to overcoming stiffness in the original system, the …

A reduced order PBM–ANN model of a multi-scale PBM–DEM description of a wet granulation process

D Barrasso, A Tamrakar, R Ramachandran - Chemical Engineering …, 2014 - Elsevier
Wet granulation is a particle design process, often used in the pharmaceutical, consumer
product, food, and fertilizer industries. A better process understanding is needed to improve …