JMH Poon, CD Immanuel, FJ Doyle Iii… - Chemical Engineering …, 2008 - Elsevier
A comprehensive model is discussed for wet granulation based on a three-dimensional population balance, as an attempt to capture particle-level phenomena and their influence …
This paper focuses on obtaining the numerical solution to a three-dimensional population balance model (PBM) of granulation using the cell-average technique first proposed by [22] …
KF Lee, M Dosta, AD McGuire, S Mosbach… - Computers & chemical …, 2017 - Elsevier
This paper presents a multi-compartment population balance model for wet granulation coupled with DEM (discrete element method) simulations. Methodologies are developed to …
Multi-dimensional population balance equations (PBEs) are commonly used to describe the dynamics of particulate processes such as granulation. Such a class of equations are …
Population balance models (PBMs) are used extensively to model various particulate processes such as granulation. A high shear granulation process is often assumed to be …
Wet granulation is a particle design process, often used in the pharmaceutical, consumer product, food, and fertilizer industries. A better process understanding is needed to improve …
T Kulju, M Paavola, H Spittka, RL Keiski… - Chemical Engineering …, 2016 - Elsevier
A multiscale modeling procedure is introduced in this paper for modeling continuous high- shear wet granulation. Flow inside the granulator is accounted using the discrete element …
CD Immanuel, FJ Doyle III - Powder Technology, 2005 - Elsevier
An efficient and novel solution technique is presented for solving multi-dimensional population balance models. In addition to overcoming stiffness in the original system, the …
Wet granulation is a particle design process, often used in the pharmaceutical, consumer product, food, and fertilizer industries. A better process understanding is needed to improve …