Objectives: To assess the diagnostic specificity of MRI-defined hippocampal atrophy for AD
among individuals with a variety of pathologically confirmed conditions associated with …

The volume of the hippocampus measured with structural magnetic resonance imaging
(MRI) is increasingly used as a biomarker for Alzheimer's disease (AD). However, the …

In this study, magnetic resonance imaging (MRI) of the hippocampus for the diagnosis of
early Alzheimer's disease (AD) is evaluated. We measured hippocampal volumes and the …

Background: Medial temporal lobe atrophy (MTA) is a sensitive radiologic marker for
Alzheimer disease (AD) and associated with cognitive impairment. The value of MTA in the …

There is compelling evidence for the early involvement of the hippocampal formation in the
natural history of Alzheimer's disease (AD). The evidence comes from recent …

The brains of patients with Alzheimer's disease (AD) invariably exhibit neuropathology in the
hippocampus and entorhinal cortex when examined postmortem. Magnetic resonance …

Hippocampal atrophy is a marker of Alzheimer disease (AD). It remains unclear whether this
holds true for younger patients as well. Hippocampal volume was measured on MRI scans …

Objective: To demonstrate structural–functional relationships between MRI-based volumetric
measurements of medial temporal lobe structures and cognitive function. Background …

The hippocampal formation (HF) is known from pathological and MRI studies to be severely
atrophied in established Alzheimer's disease. However, it is unclear when the earliest …

Age-associated memory impairment (AAMI) is a common but disputed entity. It is unclear
whether AAMI is a phenomenon of normal aging or an early sign of Alzheimer's disease …