Wide horizons of CRISPR-Cas-derived technologies for basic biology, agriculture, and medicine

KA Molla, S Karmakar, MT Islam - CRISPR-Cas methods, 2020 - Springer
The discovery and subsequent repurposing of the CRISPR (clustered regularly interspaced
short palindromic repeats) and Cas proteins (CRISPR-associated proteins) has …

Development of CRISPR-Cas systems for genome editing and beyond

F Zhang - Quarterly Reviews of Biophysics, 2019 - cambridge.org
The development of clustered regularly interspaced short-palindromic repeat (CRISPR)-Cas
systems for genome editing has transformed the way life science research is conducted and …

CRISPR-Cas systems for editing, regulating and targeting genomes

JD Sander, JK Joung - Nature biotechnology, 2014 - nature.com
Targeted genome editing using engineered nucleases has rapidly gone from being a niche
technology to a mainstream method used by many biological researchers. This widespread …

Genome modification by CRISPR/Cas9

Y Ma, L Zhang, X Huang - The FEBS journal, 2014 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR‐associated
protein (Cas) 9‐mediated genome modification enables us to edit the genomes of a variety …

The next generation of CRISPR–Cas technologies and applications

A Pickar-Oliver, CA Gersbach - Nature reviews Molecular cell biology, 2019 - nature.com
The prokaryote-derived CRISPR–Cas genome editing systems have transformed our ability
to manipulate, detect, image and annotate specific DNA and RNA sequences in living cells …

Evolution of CRISPR/cas systems for precise genome editing

M Hryhorowicz, D Lipiński, J Zeyland - International Journal of Molecular …, 2023 - mdpi.com
The bacteria-derived CRISPR/Cas (an acronym for regularly interspaced short palindromic
repeats/CRISPR-associated protein) system is currently the most widely used, versatile, and …

Potential pitfalls of CRISPR/Cas9‐mediated genome editing

R Peng, G Lin, J Li - The FEBS journal, 2016 - Wiley Online Library
Recently, a novel technique named the clustered regularly interspaced short palindromic
repeat (CRISPR)/CRISPR‐associated protein (Cas) 9 system has been rapidly developed …

CRISPR-Cas guides the future of genetic engineering

GJ Knott, JA Doudna - Science, 2018 - science.org
The diversity, modularity, and efficacy of CRISPR-Cas systems are driving a
biotechnological revolution. RNA-guided Cas enzymes have been adopted as tools to …

[HTML][HTML] CRISPR-Cas systems for genome editing, regulation and targeting

JD Sander, JK Joung - Nature biotechnology, 2014 - ncbi.nlm.nih.gov
Targeted genome editing using engineered nucleases has rapidly transformed from a niche
technology to a mainstream method used by many biological researchers. This widespread …

CRISPR/Cas9 for genome editing: progress, implications and challenges

F Zhang, Y Wen, X Guo - Human molecular genetics, 2014 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
(Cas) protein 9 system provides a robust and multiplexable genome editing tool, enabling …