Extracellular matrix (ECM) molecules play critical roles in muscle function by participating in
neuromuscular junction (NMJ) development and the establishment of stable, cytoskeleton …

The degradation of the extracellular matrix is regulated by matrix metalloproteinases (MMPs)
and tissue inhibitors of metalloproteinases (TIMPs). Matrix components of the basement …

Myogenesis in vitro involves myoblast cell cycle arrest, migration, and fusion to form
multinucleated myotubes. Extracellular matrix (ECM) integrity during these processes is …

Matrix metalloproteinases (MMPs) are zinc‐dependent proteases capable of degrading
extracellular matrix components. The activity of these proteases is tightly regulated through …

To investigate the role of tissue inhibitors of metalloproteinases (TIMPs) in muscular
dystrophy, we examined the expression of TIMP-1 using plasma and biopsied muscle from …

Objective Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a multifunctional protein that
has thc capacity to modify cellular activities and to modulate matrix turnover. This paper …

Background Tissue inhibitor of metalloproteinases-1 (TIMP-1) displays pleiotropic activities,
both dependent and independent of its inhibitory activity on matrix metalloproteinases …

Matrix metalloproteinases (MMPs) are endopeptidases that cleave matrix, soluble and
membrane-bound proteins and are regulated by their endogenous inhibitors the tissue …

Matrix metalloproteinases (MMPs) are members of an enzyme family that require a zinc ion
at their active site. Active at neutral pH, they catalyze normal turnover of extracellular matrix …

In skeletal muscles, levels and activity of Matrix MetalloProteinases (MMPs) and Tissue
Inhibitors of MetalloProteinases (TIMPs) have been involved in myoblast migration, fusion …