Where are the missing pieces of the schizophrenia genetics puzzle?

SL Girard, L Xiong, PA Dion, GA Rouleau - Current opinion in genetics & …, 2011 - Elsevier
On the basis of recent data from candidate region/gene and genome-wide association
studies (GWAS) and their follow-up investigations, the number of genes potentially …

[HTML][HTML] Schizophrenia genetics in the genome-wide era: a review of Japanese studies

T Kanazawa, CA Bousman, C Liu, IP Everall - npj Schizophrenia, 2017 - nature.com
The introduction of the genome-wide association study transformed schizophrenia genetics
research and has promoted a genome-wide mindset that has stimulated the development of …

Genetic research in schizophrenia: new tools and future perspectives

L Bertram - Schizophrenia bulletin, 2008 - academic.oup.com
Genetically, schizophrenia is a complex disease whose pathogenesis is likely governed by
a number of different risk factors. While substantial efforts have been made to identify the …

The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare …

BJ Mowry, J Gratten - Molecular psychiatry, 2013 - nature.com
After decades of halting progress, recent large genome-wide association studies (GWAS)
are finally shining light on the genetic architecture of schizophrenia. The picture emerging is …

The genetic architecture of schizophrenia: review of large-scale genetic studies

H Kato, H Kimura, I Kushima, N Takahashi… - Journal of Human …, 2023 - nature.com
Schizophrenia is a complex and often chronic psychiatric disorder with high heritability.
Diagnosis of schizophrenia is still made clinically based on psychiatric symptoms; no …

Developments in schizophrenia genetics: from linkage to microchips, deletions and duplications

HM Haraldsson, U Ettinger… - Nordic journal of …, 2011 - Taylor & Francis
Background: There is strong evidence for significant contributions of genetic factors to the
risk of schizophrenia. In the past 10 years, studies employing linkage and association …

Genetics of schizophrenia and other psychotic disorders

E Pepper, AG Cardno - Current Psychiatry Reviews, 2014 - ingentaconnect.com
Research into the genetic basis of schizophrenia is advancing rapidly. This review gives a
broad overview of results from successive phases of studies in this field, linking these with …

[HTML][HTML] Genome sequencing broadens the range of contributing variants with clinical implications in schizophrenia

BA Mojarad, Y Yin, R Manshaei, I Backstrom… - Translational …, 2021 - nature.com
The range of genetic variation with potential clinical implications in schizophrenia, beyond
rare copy number variants (CNVs), remains uncertain. We therefore analyzed genome …

Genetics of schizophrenia: ready to translate?

C Foley, A Corvin, S Nakagome - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review This is an era where we have significantly advanced the
understanding of the genetic architecture of schizophrenia. In this review, we consider how …

Genetics of schizophrenia

I Escudero, M Johnstone - Current psychiatry reports, 2014 - Springer
The genetic basis of schizophrenia has been a hotly debated research topic for decades, yet
recent studies, especially in the past year, have confirmed genetics as the major cause of …