Toward the treatment and prevention of Alzheimer's disease: rational strategies and recent progress

S Gandy, ST DeKosky - Annual review of medicine, 2013 - annualreviews.org
Alzheimer's disease (AD) is the major cause of late-life brain failure. In the past 25 years,
autosomal dominant forms of AD were found to be primariy attributable to mutations in one …

[HTML][HTML] Advances in the prevention of Alzheimer's Disease

S Sindi, F Mangialasche, M Kivipelto - F1000prime reports, 2015 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), the leading cause of dementia, has reached epidemic
proportions, with major social, medical and economical burdens. With no currently available …

Primary and secondary prevention trials in Alzheimer disease: looking back, moving forward

D Hsu, GA Marshall - Current Alzheimer Research, 2017 - ingentaconnect.com
The field of Alzheimer disease (AD) prevention has been a culmination of basic science,
clinical, and translational research. In the past three years since the new 2011 AD diagnostic …

Risk factors and preventive interventions for Alzheimer disease: state of the science

ML Daviglus, BL Plassman, A Pirzada… - Archives of …, 2011 - jamanetwork.com
Background Numerous studies have investigated risk factors for Alzheimer disease (AD).
However, at a recent National Institutes of Health State-of-the-Science Conference, an …

The present and future of pharmacotherapy of Alzheimer's disease: A comprehensive review

A Anand, AA Patience, N Sharma, N Khurana - European journal of …, 2017 - Elsevier
Alzheimer's disease (AD) is a generalized term used for the loss in memory and other
intellectual abilities on levels serious enough to interfere with daily life. It accounts for 60 …

[PDF][PDF] Alzheimer's disease: Causes & treatment–A review

I Bhushan, M Kour, G Kour, S Gupta, S Sharma… - Ann …, 2018 - academia.edu
Alzheimer's disease is an unavoidable neurological disorder in which the death of brain
cells causes memory loss and cognitive decline and ultimate dementia. It is the most …

Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease

T Athar, K Al Balushi, SA Khan - Molecular biology reports, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative old age disease that is complex,
multifactorial, unalterable, and progressive in nature. The currently approved therapy …

Slowing the progression of Alzheimer's disease; what works?

L Nelson, N Tabet - Ageing research reviews, 2015 - Elsevier
Alzheimer's disease (AD) is an age-related progressive dementia, which is increasing in
prevalence world-wide. Typically affecting short-term memory at onset, this devastating …

[PDF][PDF] Pathophysiology and management of Alzheimer's disease: An overview

AK Thakur, P Kamboj, K Goswami, K Ahuja - J anal pharm Res, 2018 - researchgate.net
Alzheimer's disease (AD) is the sixth-leading reason of fatality and is 70% present in all
cases of dementia. The global burden of AD is expected to accelerate from 26.6 million …

The emerging role of nutraceuticals and phytochemicals in the prevention and treatment of Alzheimer's disease

C Calfio, A Gonzalez, SK Singh… - Journal of …, 2020 - content.iospress.com
One of the major challenges of medical sciences has been finding a reliable compound for
the pharmacological treatment of Alzheimer's disease (AD). As most of the drugs directed to …