Current understanding of the physiopathology, diagnosis and therapeutic approach to Alzheimer's disease

V García-Morales, A González-Acedo… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia. It is characterized by
cognitive decline and progressive memory loss. The aim of this review was to update the …

New treatment strategies for Alzheimer's disease: is there a hope?

I Aprahamian, F Stella, OV Forlenza - Indian Journal of Medical …, 2013 - journals.lww.com
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease, and
corresponds to the most common cause of dementia worldwide. Although not fully …

Alzheimer's disease therapeutic approaches

M Revi - GeNeDis 2018: Genetics and Neurodegeneration, 2020 - Springer
Alzheimer's disease (AD) was first described and diagnosed by Dr. Alois Alzheimer in 1906
(Hippius and Neundorfer, Dialogues Clin Neurosc 5: 101–108, 2003). According to World …

Two decades of new drug discovery and development for Alzheimer's disease

Z Liu, A Zhang, H Sun, Y Han, L Kong, X Wang - RSC advances, 2017 - pubs.rsc.org
Alzheimer's disease is a progressive and irreversible neurodegenerative disease,
associated with a decreased cognitive function and severe behavioral abnormalities. Due to …

[HTML][HTML] Antidiabetic agents as a novel treatment for Alzheimer's and Parkinson's disease

J Nowell, E Blunt, D Gupta, P Edison - Ageing Research Reviews, 2023 - Elsevier
Therapeutic strategies for neurodegenerative disorders have commonly targeted individual
aspects of the disease pathogenesis to little success. Neurodegenerative diseases …

Drug candidates in clinical trials for Alzheimer's disease

SY Hung, WM Fu - Journal of biomedical science, 2017 - Springer
Alzheimer's disease (AD) is a major form of senile dementia, characterized by progressive
memory and neuronal loss combined with cognitive impairment. AD is the most common …

[HTML][HTML] An update on the novel and approved drugs for Alzheimer disease

HA Alhazmi, M Albratty - Saudi Pharmaceutical Journal, 2022 - Elsevier
Introduction Given the severity of the condition and the increasing number of patients,
developing effective therapies for Alzheimer's disease has become a significant necessity …

Alzheimer disease and its management: a review

MK Samanta, B Wilson, K Santhi… - American journal of …, 2006 - journals.lww.com
Alzheimer disease is a progressive degenerative disorder of the brain characterized by a
slow, progressive decline in cognitive function and behavior. As the disease advances …

Pharmacotherapies for Alzheimer's disease: beyond cholinesterase inhibitors

HO Tayeb, HD Yang, BH Price, FI Tarazi - Pharmacology & therapeutics, 2012 - Elsevier
Alzheimer's disease (AD) is the most common cause of memory impairment and dementia in
the elderly. AD is pathologically characterized by extracellular deposits of beta-amyloid (Aβ) …

A review on advances of treatment modalities for Alzheimer's disease

ES Thoe, A Fauzi, YQ Tang, S Chamyuang, AYY Chia - Life sciences, 2021 - Elsevier
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease which is mainly
characterized by progressive impairment in cognition, emotion, language and memory in …