Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with abundant
adipocytokine changes which may play an important role in the progression of insulin …

Background The objective of this study was to assess the effects of metformin monotherapy
or combined treatment with a dipeptidyl peptidase-4 inhibitor (vildagliptin) on apelin levels in …

Objective: To investigate blood apelin concentrations in patients with newly diagnosed and
untreated type 2 diabetes mellitus (T2DM) who had no additional disorder and to investigate …

Aims Apelin is a circulatory blood peptide acting as a ligand for the orphan G protein-
coupled receptor known as APJ. Whether apelin blood levels can affect the pathogenesis of …

Background Apelin is an adipokine that plays a role in the regulation of glucose
homeostasis and in obesity. The relationship between apelin serum concentration and …

Background The physiological role of apelin in obesity and diabetes remains unclear.
Although apelin has been studied in persons with different conditions, no studies have yet …

Purpose Apelin is an adipokine that plays a role in the regulation of many biological
functions in mammals including the neuroendocrine, cardiovascular, immune systems …

Context Apelin is an adipokine expressed in several tissues and it appears to be involved in
energy metabolism. Objective The aim of this study was to determine serum apelin levels in …

Background Apelin regulates insulin sensitivity and secretion in animals. However, whether
plasma apelin predicts incident diabetes in humans remains unknown. Methods We studied …

Apelin is proposed to possess protective cardiovascular properties and may furthermore
promote favorable effects on glucose metabolism. First data in humans seem to support this …