Computer models of arterial trees can be generated from optimization principles using the
algorithm of constrained constructive optimization (CCO). Up to now this algorithm could …

There is a marked difference in the structure of the arterial tree between epi-and endocardial
layers of the human heart. To model these structural variations, we developed an extension …

The computational method of constrained constructive optimization (CCO) has been
generalized in two important respects:(1) arterial model trees are now grown within a …

Models of coronary arterial trees are generated by the algorithm of constrained constructive
optimization (CCO). In a given perfusion area a binary branching network of straight …

The computational method of constrained constructive optimization was used to generate
complex arterial model trees by optimization with respect to a target function. Changing the …

We present a framework for the construction of vascular systems based on optimality
principles of theoretical physiology. Given the position and flow distribution of end points of a …

Arterial tree models are generated by Constrained Constructive Optimization according to
minimum intravascular volume. These models, which have been shown to adequately …

Models of arterial trees are generated by the algorithm of Constrained Constructive
Optimization (CCO). Straight cylindrical, binary branching tubes are arranged in an …

Topological and metric properties of Voronoi polyhedra (VP) generated by the distal end
points of terminal segments in arterial tree models grown by the method of constrained …

We study various properties of constructive optimization in 3D vascular systems. After some
remarks on existing approaches to vascular modeling and on the theory of vascular …