Understanding the burden of pneumococcal disease in adults

F Blasi, M Mantero, PA Santus… - Clinical Microbiology and …, 2012 - Wiley Online Library
Clin Microbiol Infect 2012; 18 (Suppl. 5): 7–14 Abstract Streptococcus pneumoniae causes
different types of acute, invasive and non‐invasive clinical infections, being the most …

Pneumococcal infection in adults: burden of disease

JJC Drijkoningen, GGU Rohde - Clinical Microbiology and …, 2014 - Wiley Online Library
To overview the present global burden of pneumococcal disease is important because new
preventive measures such as the pneumococcal conjugate vaccine 13 are currently being …

[HTML][HTML] Pneumococcal vaccination: what have we learnt so far and what can we expect in the future?

A Torres, P Bonanni, W Hryniewicz… - European Journal of …, 2015 - Springer
Individuals< 2 years and≥ 50 years of age, as well as those with other specific risk factors,
are especially vulnerable to invasive pneumococcal disease (IPD). Conjugate vaccines …

Adult vaccination for pneumococcal disease: a comparison of the national guidelines in Europe

C Bonnave, D Mertens, W Peetermans… - European Journal of …, 2019 - Springer
Pneumococcal disease constitutes a major global health problem. Adults aged over 50
years and younger adults with specific chronic health conditions are at risk for invasive …

Rates of pneumococcal disease in adults with chronic medical conditions

KM Shea, J Edelsberg, D Weycker… - Open forum …, 2014 - academic.oup.com
Background. Although it is widely accepted that adults with immunocompromising conditions
are at greatly increased risk of pneumococcal infection, the extent of risk among …

[HTML][HTML] Prevention of pneumococcal diseases in the post-seven valent vaccine era: a European perspective

C Weil-Olivier, M van der Linden, I De Schutter… - BMC infectious …, 2012 - Springer
Background The burden of invasive pneumococcal disease in young children decreased
dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) …

[HTML][HTML] Pneumonia and invasive pneumococcal diseases: the role of pneumococcal conjugate vaccine in the era of multi-drug resistance

C Scelfo, F Menzella, M Fontana, G Ghidoni… - Vaccines, 2021 - mdpi.com
Streptococcus pneumoniae related diseases are a leading cause of morbidity and mortality,
especially in children and in the elderly population. It is transmitted to other individuals …

First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial

AM Collins, AD Wright, E Mitsi, JF Gritzfeld… - American journal of …, 2015 - atsjournals.org
Rationale: New vaccines are urgently needed to protect the vulnerable from bacterial
pneumonia. Clinical trials of pneumonia vaccines are slow and costly, requiring tens of …

Pneumococcal vaccination: current and future issues

Å Örtqvist - European Respiratory Journal, 2001 - Eur Respiratory Soc
Infection with Streptococcus pneumoniae remains a major global health burden meaning
the development of effective vaccines is urgently needed. The current 23-valent …

[HTML][HTML] Epidemiology, virulence factors and management of the pneumococcus

C Feldman, R Anderson - F1000Research, 2016 - ncbi.nlm.nih.gov
Pneumococcal infections continue to cause significant morbidity and mortality in patients
throughout the world. This microorganism remains the most common bacterial cause of …