OBJECTIVE Recent data suggested that sex hormone–binding globulin (SHBG) levels
decrease when fat accumulates in the liver and that circulating SHBG may be causally …

Background Sex hormone-binding globulin (SHBG) levels and sex hormones have been
implicated in the pathogenesis of type 2 diabetes and cardiovascular diseases. As fatty liver …

Hepatic sex-hormone binding globulin (SHBG) production is down-regulated by insulin and
low levels reflect insulin resistance. Because insulin resistance is closely related to the …

The level of sex hormone-binding globulin (SHBG) is associated with glucose metabolism in
nondiabetic women and men, and the finding of low SHBG levels is suggested to be a …

Context: The plasma level of sex hormone binding globulin (SHBG), a glycoprotein
produced by hepatocytes, is subject to genetic, hormonal, metabolic, and nutritional …

Low plasma sex hormone–binding globulin (SHBG) levels are associated with obesity and
predict the development of type 2 diabetes. The reason why obese individuals have low …

Objective Previous evidence has suggested that a low sex hormone-binding globulin
(SHBG) concentration is associated with insulin-resistance and a low adiponectin …

OBJECTIVE Sex hormone-binding globulin (SHBG) has been shown to be associated with
several diabetes risk factors, including total body fat, central obesity, and hyperinsulinemic …

Serum sex hormone–binding globulin (SHBG) is related to cardiometabolic disorders; but
whether or not this relationship is purely secondary to hyperinsulinemia and/or obesity …

Sex hormone-binding globulin (SHBG) has emerged as one of the multiple genetic and
environmental factors that potentially contribute to the pathophysiology of type 2 diabetes …