Stem Cell Therapy for the Treatment of Parkinson's Disease: What Promise Does it Hold?

A Nasrolahi, Z Shabani… - Current Stem Cell …, 2024 - ingentaconnect.com
Parkinson's disease (PD) is a common, progressive neurodegenerative disorder
characterized by substantia nigra dopamine cell death and a varied clinical picture that …

An update on human stem cell-based therapy in Parkinson's disease

C González, S Bonilla, A Isabel Flores… - Current stem cell …, 2016 - ingentaconnect.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease and it is characterized by the progressive loss of dopaminergic neurons …

[HTML][HTML] Stem cell treatments for Parkinson's disease

TB Stoker - 2019 - europepmc.org
Parkinson's disease (PD) manifests with a typical movement disorder, due to the loss of
dopaminergic neurons of the substantia nigra. There are no disease-modifying treatments …

Current state of stem cell research for the treatment of Parkinson's disease

M Gerlach, H Braak, A Hartmann, WH Jost, P Odin… - Journal of …, 2002 - Springer
Current findings suggest that multipotent stem cells may be suitable for cell replacement
therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are …

From bench to bed: the potential of stem cells for the treatment of Parkinson's disease

A Morizane, JY Li, P Brundin - Cell and tissue research, 2008 - Springer
Parkinson's disease (PD) is the most common movement disorder. The neuropathology is
characterized by the loss of dopamine neurons in the substantia nigra pars compacta …

Stem cell-based therapies in Parkinson's disease: future hope or current treatment option?

K Loewenbrück, A Storch - Journal of neurology, 2011 - Springer
Parkinson's disease (PD) is one of the most frequent neurodegenerative diseases and
represents a major therapeutic challenge because of the so far missing therapeutic means …

Stem cells and regenerative therapies for Parkinson's disease

K Farrell, RA Barker - Degenerative Neurological and …, 2012 - Taylor & Francis
Currently the mainstay of Parkinson's disease (PD) therapy is the pharmacological
replacement of the loss of the dopaminergic nigrostriatal pathway using drugs such as …

Overcoming Methodological Challenges for Advancing Stem Cell Therapies in Parkinson's Disease

S Polgar, DI Finkelstein, L Karimi - Cell Transplantation, 2024 - journals.sagepub.com
The quest for new and improved therapies for Parkinson's disease (PD) remains of
paramount importance, despite previous trial failures. There is a current debate regarding …

Clinical application of stem cell therapy in Parkinson's disease

M Politis, O Lindvall - BMC medicine, 2012 - Springer
Cell replacement therapies in Parkinson's disease (PD) aim to provide long-lasting relief of
patients' symptoms. Previous clinical trials using transplantation of human fetal ventral …

The challenges of administering cell-based therapies to patients with Parkinson's disease

J Drouin-Ouellet, RA Barker - NeuroReport, 2013 - journals.lww.com
Although the concept of cell-based therapy for Parkinson's disease has been around for
more than three decades with proof-of-concept studies in man having been achieved, it still …