C González, S Bonilla, A Isabel Flores… - Current stem cell …, 2016 - ingentaconnect.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease and it is characterized by the progressive loss of dopaminergic neurons …
Parkinson's disease (PD) manifests with a typical movement disorder, due to the loss of dopaminergic neurons of the substantia nigra. There are no disease-modifying treatments …
M Gerlach, H Braak, A Hartmann, WH Jost, P Odin… - Journal of …, 2002 - Springer
Current findings suggest that multipotent stem cells may be suitable for cell replacement therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are …
A Morizane, JY Li, P Brundin - Cell and tissue research, 2008 - Springer
Parkinson's disease (PD) is the most common movement disorder. The neuropathology is characterized by the loss of dopamine neurons in the substantia nigra pars compacta …
K Loewenbrück, A Storch - Journal of neurology, 2011 - Springer
Parkinson's disease (PD) is one of the most frequent neurodegenerative diseases and represents a major therapeutic challenge because of the so far missing therapeutic means …
K Farrell, RA Barker - Degenerative Neurological and …, 2012 - Taylor & Francis
Currently the mainstay of Parkinson's disease (PD) therapy is the pharmacological replacement of the loss of the dopaminergic nigrostriatal pathway using drugs such as …
The quest for new and improved therapies for Parkinson's disease (PD) remains of paramount importance, despite previous trial failures. There is a current debate regarding …
Cell replacement therapies in Parkinson's disease (PD) aim to provide long-lasting relief of patients' symptoms. Previous clinical trials using transplantation of human fetal ventral …
Although the concept of cell-based therapy for Parkinson's disease has been around for more than three decades with proof-of-concept studies in man having been achieved, it still …