There is growing evidence that nitric oxide serves as a neurotransmitter released from
enteric inhibitory nerves in the gastrointestinal tract. The distribution of nitric oxide synthase …

The immunohistochemical localization of cyclic GMP was used to determine potential
physiological sites of action of nitric oxide in the guinea-pig small intestine and colon. In …

Nitric oxide (NO) may serve as a non-adrenergic, non-cholinergic (NANC) neurotransmitter
released from enteric inhibitory nerves in the gastrointestinal tract. We tested whether …

Previous studies suggested that nitric oxide (NO) may cause hyperpolarization and
relaxation of canine colonic smooth muscle by both cGMP-dependent and cGMP …

In this work we describe a region of mouse intestine, the caecum, in which inhibitory
transmission to the longitudinal muscle is predominantly due to nitric oxide. In the presence …

The nitric oxide (NO) signaling pathway is a major nonadrenergic-noncholinergic transmitter
mechanism in the enteric nervous system. Our aim was to localize the enzymes in question …

This study examined the mechanism through which nitric oxide inhibits the release of
acetylcholine and excitatory motor neurotransmission in the guinea-pig ileum. The selective …

Conclusions The evidence is very strong that NO serves as a neurotransmitter in some
autonomic neurons. In the canine proximal colon, NOS is localized in fibers and varicosities …

Vasoactive intestinal peptide release and l-[3 H] citrulline production were examined in
ganglia isolated from the myenteric plexus of guinea-pig intestine. The nicotinic agonist, 1, 1 …

Nitric oxide has been put forward as an important inhibitory neurotransmitter in the gut. Nitric
oxide synthase-containing neurons were visualized by immunocytochemistry using …