Effects of polymorphisms in β1-adrenoceptor and α-subunit of G protein on heart rate and blood pressure during exercise test. The Finnish Cardiovascular Study
T Nieminen, T Lehtimaki, J Laiho… - Journal of Applied …, 2006 - journals.physiology.org
We tested whether the Arg389Gly and Ser49Gly polymorphisms of the β1-adrenergic
receptor gene ADRB1 and the T393C polymorphism of the G protein α-subunit gene GNAS1 …
receptor gene ADRB1 and the T393C polymorphism of the G protein α-subunit gene GNAS1 …
β1-adrenergic receptor polymorphisms: a possible genetic predictor of bisoprolol response in acute coronary syndrome
Aim: To investigate the association between beta1-adrenergic receptor (ADRB1)
polymorphisms and response to bisoprolol treatment in beta-blocker naive patients with …
polymorphisms and response to bisoprolol treatment in beta-blocker naive patients with …
[HTML][HTML] The association of ADRB1 and CYP2D6 polymorphisms with antihypertensive effects and analysis of their contribution to hypertension risk
L Chen, T Xiao, L Chen, S Xie, M Deng, D Wu - The American Journal of …, 2018 - Elsevier
Background Genetic factors have a vital influence on the pathogenesis of hypertension. In
this retrospective study, we aimed to evaluate the association of ADRB1 and CYP2D6 …
this retrospective study, we aimed to evaluate the association of ADRB1 and CYP2D6 …
Genetic polymorphisms in ADRB2 and ADRB1 are associated with differential survival in heart failure patients taking β-blockers
LA Guerra, C Lteif, MJ Arwood… - The …, 2022 - nature.com
Single nucleotide polymorphisms (SNPs) have been associated with differential beta-
blocker (BB) effects on heart rate, blood pressure, and left ventricular ejection fraction in …
blocker (BB) effects on heart rate, blood pressure, and left ventricular ejection fraction in …
Pharmacogenetics may explain part of the interindividual variability of dobutamine pharmacodynamics in neonates
Aims To determine whether the known single nucleotide polymorphisms in adrenoreceptor
associated genes affect the haemodynamic response to dobutamine in critically ill neonates …
associated genes affect the haemodynamic response to dobutamine in critically ill neonates …
[HTML][HTML] Genetic associations of bradykinin type 2 receptor, alpha-adrenoceptors and endothelial nitric oxide synthase with blood pressure and left ventricular mass in …
Background Physiological pathways such as bradykinin, renin-angiotensin, neurohormones
and nitric oxide have been shown to play an important role in the regulation of …
and nitric oxide have been shown to play an important role in the regulation of …
Association of β-adrenergic receptor genes polymorphisms with incidence of subsequent cardiovascular events in Han Chinese patients with coronary artery disease
ZG Li, WU Hong, Y Zhou, ZJ Chen, JX Meng… - Chinese medical …, 2013 - journals.lww.com
Background Sequence variants in the β-adrenergic receptor (ADRB) genes have a close
relationship with the development of coronary artery disease (CAD) and the patient's …
relationship with the development of coronary artery disease (CAD) and the patient's …
[PDF][PDF] β-1-adrenoreceptor gene polymorphism role in the development of dilated cardiomyopathy
OO Kuznetsova, SY Nikulina… - РМЖ …, 2020 - rusmedreview.com
Aim: to identify patterns of development of idiopathic dilated cardiomyopathy (IDC) and
ischemic cardiomyopathy (ICM) by studying the rs 1801252 (Ser49Gly) polymorphic variant …
ischemic cardiomyopathy (ICM) by studying the rs 1801252 (Ser49Gly) polymorphic variant …
ADRB1 gene polymorphism regulated the positive inotropic effect of myocardial insufficiency with metabolic syndrome: a basic experimental research
R Liu, F Yang, P Wang, X Zhao, W Wu, H Ma, Y Zhao… - 2024 - researchsquare.com
Background The risk of cardiovascular disease (CVD) in metabolic syndrome (MS) patients
is significantly higher than that in healthy people, and ADRB1 gene polymorphism is closely …
is significantly higher than that in healthy people, and ADRB1 gene polymorphism is closely …
Arginine 16 glycine β2-adrenoceptor polymorphism and cardiovascular structure and function in patients with heart failure
R Wolk, EM Snyder, VK Somers, ST Turner… - Journal of the American …, 2007 - Elsevier
The β2/β1 adrenoceptor ratio increases in congestive heart failure (CHF), making the heart
relatively more dependent on inotropic, lusitropic, and chronotropic stimulation by the β2 …
relatively more dependent on inotropic, lusitropic, and chronotropic stimulation by the β2 …