The β1-adrenoceptor gene (ADBR1) exhibits a frequent SNP that causes a change of Arg at
position 389 to Gly [6]. Approximately 40 and 7% of Caucasians are heterozygous and …

Background Sympathetic activation in heart failure patients favors the development of
ventricular arrhythmias, thus leading to an increased risk of sudden cardiac death. β1‐and …

Summary β-adrenergic receptors (β-ARs) play a pivotal role in the cardiovascular regulation.
In the human heart β 1-and β 2-ARs dominate in atria as well as in ventricle influencing …

Background Ventricular arrhythmia is a common complication of acute myocardial infarction
(AMI). The Arg389Gly polymorphism of the β1-adrenergic receptor genotype may affect AMI …

Objective: Coronary artery disease (CAD) is a the most common type of heart disease, and
is associated with the highest mortality rate. The role of the β3-adrenergic receptor gene …

Objectives: The purpose of this research was to find out whether, in humans, dobutamine-
induced hemodynamic effects and increase in plasma-renin activity (PRA) might be beta1 …

Abstract β-blockers are commonly prescribed to treat multiple cardiovascular (CV) diseases,
but, frequently, adverse drug reactions and intolerance limit their use in clinical practice …

BACKGROUND: The β1-and β2-adrenergic receptors (ARs) coexist in the human heart and
control sympathetic responses. Several functional genetic variations in the β-AR genes …

Background: There is considerable variability in individual response to antihypertensive
agents. The reason for this is not known, but may be related to individual genetic variability …

Common naturally occurring polymorphisms have been identified in the coding regions of
the α1A-, α2B-, β1-and β2-adrenoceptor (AR) genes [α1A-AR R492C, α2B-AR …