Beta-adrenoreceptors genetic polymorphism connection with beta-bloker therapy efficacy in patients with cardiovascular disorders

AN Levanov, IV Ignatyev, DA Sychev… - Saratov Journal of …, 2009 - ssmj.ru
At present it is obvious that genetic peculiarities of patients are the major reason for
individual differences in pharmacological responses to (?-adrenoblockers. Furthermore …

Impact of CYP2D6 and ADRB1 polymorphisms on heart rate of post-PCI patients treated with metoprolol

X Gao, H Wang, H Chen - Pharmacogenomics, 2017 - Taylor & Francis
Aim: To explore the effect of CYP2D6* 10 (100C> T) and ADRB1 1165 G> C polymorphisms
on heart rate of post-PCI (percutaneous coronary intervention) patients treated with …

Evaluation of cardiac beta-adrenergic receptor function in children by dobutamine stress echocardiography

H ZENG, W LI, Y LI, YDUJ MA - Chinese medical journal, 1999 - mednexus.org
OBJECTIVE To investigate the role of dobutamine stress echocardiography in evaluating
cardiac β-adrenergic receptor (β-AR) function and responsiveness in children. METHODS …

Studies of associations between the Arg389Gly polymorphism of the β1‐adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white …

AP Gjesing, G Andersen, A Albrechtsen… - Diabetic …, 2007 - Wiley Online Library
Aims Activation of the β1‐adrenergic receptor (ADRB1) causes increased lipolysis in
adipose tissue and enhances cardiac output. Analysis of the association of the functional …

Association of genetic polymorphisms in the beta-1 adrenergic receptor with recovery of left ventricular ejection fraction in patients with heart failure

JA Luzum, JD English, US Ahmad, JW Sun… - Journal of …, 2019 - Springer
Two common genetic polymorphisms in the beta-1 adrenergic receptor (ADRB1 Ser49Gly
[rs1801252] and Arg389Gly [rs1801253]) significantly affect receptor function in vitro. The …

Impact of neuroeffector adrenergic receptor polymorphisms on incident ventricular fibrillation during acute myocardial ischemia

P Chevalier, P Roy, F Bessière, E Morel… - Journal of the …, 2023 - Am Heart Assoc
Background Cardiac adrenergic receptor gene polymorphisms have the potential to
influence risk of developing ventricular fibrillation (VF) during ST‐segment‐elevation …

Genetic polymorphism of beta-adrenergic receptors and mortality in ischemic heart disease

P Jaillon, T Simon - Therapie, 2007 - europepmc.org
The genetic polymorphism of beta-2 adrenergic receptors (B2AR) could play a major role in
the prognostic of patients with a coronary heart disease. Two recent epidemiological studies …

[HTML][HTML] The role of ADRB1 genes polymorphism in examined patients with chronic rheumatic heart disease

VS Petrov, EA Smirnova - Problems of Social Hygiene, Public Health …, 2019 - journal-nriph.ru
The study purpose is to evaluate effect of ADRB1 gene polymorphism on echocardiography
indices and endothelial function in patients with chronic rheumatic heart disease. The …

Association of the beta-1 adrenergic receptor carboxyl terminal variants with left ventricular hypertrophy among diabetic and non-diabetic survivors of acute …

AE Hakalahti, JM Tapanainen, JM Junttila… - Cardiovascular …, 2010 - Springer
Background The beta-1 adrenergic receptor (β 1 AR) plays a fundamental role in the
regulation of cardiovascular functions. It carries a nonsynonymous single nucleotide …

[HTML][HTML] CYP2D6 and ADRB1 genetic polymorphisms and the selection of antihypertensive beta-receptor blockers for hypertensive patients

K Chen, Y Li, C Yang, P Xiao, G Li… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Genetic factors contribute to the variability in individual response to
antihypertensive medications. We sought to investigate the frequencies of allele and …