Impact of the β1‐adrenoceptor Arg389Gly polymorphism on heart‐rate responses to Bisoprolol and carvedilol in heart‐failure patients

T Rau, HD Düngen, F Edelmann… - Clinical …, 2012 - Wiley Online Library
This pharmacogenetic substudy of the prospective, double‐blind, randomized CIBIS‐ELD
trial determined the impact of the β1‐adrenoceptor Arg189Gly polymorphism on heart‐rate …

Original articles Polymorphisms of the beta-1 and beta-2 adrenergic receptors in Polish patients with idiopathic dilated cardiomyopathy

A Pączkowska, M Szperl, ŁA Małek… - Polish Heart …, 2009 - journals.viamedica.pl
Background: Dilated cardiomyopathy (DCM) is a disorder characterised by dilation and
impaired contractility of the left or both ventricles. This multifactorial disease has a strong …

Angiotensin-converting enzyme gene polymorphism in arrhythmogenic right ventricular dysplasia: is DD genotype helpful in predicting syncope risk?

B Ozben, I Altun, V Sabri Hancer… - Journal of the Renin …, 2008 - journals.sagepub.com
Introduction. Arrhythmogenic right ventricular dysplasia (ARVD) is a heritable disorder
characterised by fibrofatty replacement of right ventricular myocytes and increased risk of …

Expression of the β1-adrenergic receptor (ADRB1) gene in the myocardium and β-adrenergic reactivity of the body in patients with a history of myocardium infraction

E Muslimova, T Rebrova, D Kondratieva, V Korepanov… - Gene, 2022 - Elsevier
Abstract β1-adrenergic receptors (β1-AR) directly affect on intracardiac hemodynamic and
the ability of the heart to tolerate physical activity by regulating its inotropic and chronotropic …

[PDF][PDF] Association of the ADRB2 gene polymorphic variant C79G (rs1072714) with the course of chronic obstructive pulmonary disease in obese and non-obese …

G Stupnytska, N Gorovenko… - CBU International …, 2018 - pdfs.semanticscholar.org
Introduction: Attention has been paid to studying the role of the sympathetic nervous system
and polymorphism of the β2-adrenoceptor genes in the development of chronic obstructive …

A46G and C79G polymorphisms in the β2-adrenergic receptor gene (ADRB2) and essential hypertension risk: a meta-analysis

Y Lou, J Liu, Y Huang, J Liu, Z Wang, Y Liu, Z Li… - Hypertension …, 2010 - nature.com
No consensus has been reached on the association between the β2-adrenergic receptor
polymorphisms A46G and C79G and essential hypertension risk. We performed a meta …

Impact of renin–angiotensin–aldosterone system polymorphisms on myocardial perfusion: Correlations with myocardial single photon emission computed tomography …

G Angelidis, M Samara, M Papathanassiou… - Journal of Nuclear …, 2019 - Elsevier
Background Renin–angiotensin–aldosterone system (RAAS) has an important role in
atherosclerosis. We investigated the effects of six RAAS gene polymorphisms on myocardial …

Investigating genetic variation of adrenergic receptors in familial stress cardiomyopathy (apical ballooning syndrome)

AD Handy, A Prasad, TM Olson - Journal of cardiology, 2009 - journal-of-cardiology.com
In their recently published article, Sharkey et al.[1] genotyped three adrenergic receptor
polymorphisms in a cohort of 41 patients with stress cardiomyopathy (SC). This idiopathic …

Association Analysis of β2-Adrenergic Receptor Polymorphisms With Hypertension in Japanese

N Kato, T Sugiyama, H Morita, H Kurihara, T Sato… - …, 2001 - Am Heart Assoc
Significant evidence has been provided for the pathophysiological involvement of the β2-
adrenergic receptor (ADRB2) in hypertension. Among ADRB2 polymorphisms identified to …

Twelve novel single nucleotide polymorphisms in ABCB1/MDR1 among Japanese patients with ventricular tachycardia who were administered amiodarone

M Itoda, Y Saito, K Komamura, K Ueno… - Drug metabolism and …, 2002 - jstage.jst.go.jp
Twelve novel single nucleotide polymorphisms (SNPs) were found in the gene encoding the
ATPbinding cassette transporter, Pglycoprotein, from 60 Japanese individuals who were …