Parkinson's disease: Current drug therapy and unraveling the prospects of nanoparticles

A Paul, KS Yadav - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Abstract Parkinson's disease (PD), although being the second most prevalent
neurodegenerative disease (ND) encounters lack of definitive treatment and challenges in …

Deciphering the role of nanoparticle-based treatment for Parkinson's disease

MMR Moni, M Begum, MS Uddin… - Current Drug …, 2021 - ingentaconnect.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder that exerts a huge
burden on our society. The occurrence of this neurodegenerative disease has been …

Potential applications of nanomedicine for treating Parkinson's disease

J Shankar, KM Geetha, B Wilson - Journal of Drug Delivery Science and …, 2021 - Elsevier
Parkinson's disease (PD) is an extrapyramidal, chronic progressive neurodegenerative
disorder. It affects approximately 5 million individuals globally, and by 2030, the prevalence …

Importance of nanoparticles for the delivery of antiparkinsonian drugs

S Silva, AJ Almeida, N Vale - Pharmaceutics, 2021 - mdpi.com
Parkinson's disease (PD) affects around ten million people worldwide and is considered the
second most prevalent neurodegenerative disease after Alzheimer's disease. In addition …

[PDF][PDF] Emerging promise of nanoparticle-based treatment for Parkinson's disease

MM Rahman, KS Ferdous… - Biointerface Res. Appl …, 2020 - biointerfaceresearch.com
Neurodegenerative disorders are consequences of the deterioration of cells and tissues with
a mature undesirable way of life. The degenerative disease like Parkinson's disease (PD) …

Drug development in Parkinson's disease: from emerging molecules to innovative drug delivery systems

E Garbayo, E Ansorena, MJ Blanco-Prieto - Maturitas, 2013 - Elsevier
Current treatments for Parkinson's disease (PD) are aimed at addressing motor symptoms
but there is no therapy focused on modifying the course of the disease. Successful treatment …

Nanoparticle technology for treatment of Parkinson's disease: the role of surface phenomena in reaching the brain

G Leyva-Gomez, H Cortes, JJ Magana… - Drug discovery today, 2015 - Elsevier
Highlights•We describe the main clinical manifestations and pathogenesis of Parkinson's
disease.•We present a general overview of current treatments for Parkinson's disease.•We …

Nanotechnology driven approaches for the management of Parkinson's disease: current status and future perspectives

S Sharma, SA Rabbani, T Agarwal… - Current drug …, 2021 - ingentaconnect.com
Parkinson's disease (PD) is believed to be one of the commonly found adult-onset
movement disorder occurring due to neurodegeneration and striatal dopamine deficiency …

Nanomedicine to overcome current Parkinson's treatment liabilities: A systematic review

GH Hawthorne, MP Bernuci, M Bortolanza… - Neurotoxicity …, 2016 - Springer
Nanoparticles might be produced and manipulated to present a large spectrum of
properties. The physicochemical features of the engineered nanomaterials confer to them …

Nanoparticles for drug delivery in Parkinson's disease

J Baskin, JE Jeon, SJG Lewis - Journal of Neurology, 2021 - Springer
Although effective symptomatic treatments for Parkinson's disease (PD) have been available
for some time, efficient and well-controlled drug delivery to the brain has proven to be …